SMU1 Antibodies

AND SMU1 ELISA kits, SMU1 Proteins

Many biological assays use antibodies to detect SMU1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SMU1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SMU1 antibodies...

We validate the specificity of these antibodies to SMU1 by testing them on tissues known to express SMU1 positively and negatively. Browse below to find the SMU1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SMU1 Infographic by Boster Bio

All SMU1 Products

Product

Figures

Specificity

Applications

Price

Anti-SMU1 Antibody

Human, Mouse, Rat

$405
Cat # A12946
100ul

SMU1 (NM_018225) Human Recombinant Protein

$1249
Cat # PROTQ2TAY7
20 µg

SMU1 (NM_018225) Human Over-expression Lysate

Human

$628
Cat # LS055234
100 µg

SMU1 Overview

Facts about WD40 repeat-containing protein SMU1.

SMU1 3D structure. Source: alphafold

WD40 repeat-containing protein SMU1 (SMU1)

Auxiliary spliceosomal protein which modulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity).

Required for normal mitotic spindle assembly and regular progress through mitosis (PubMed:15878348). Required for normal accumulation of IK (PubMed:24945353).

Gene Information

Human
Gene Name:	SMU1
Uniprot:	Q2TAY7
Entrez:	55234

Family

Belongs to:

WD repeat SMU1 family

Alternative Names

brain-enriched WD-repeat protein; BWD; DKFZp761L0916; FLJ10805; FLJ10870; FLJ11970; fSAP57; functional spliceosome-associated protein 57; MGC117363; RP11-54K16.3; smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans); Smu-1 suppressor of mec-8 and unc-52 protein homolog; SMU-1; WD40 repeat-containing protein SMU1

Molecular Weight

Mass (kDA):
57.544 kDA

Genomic Context


Human

Location:	9p21.1
Sequence:	9; NC_000009.12 (33041765..33076705, complement)

Subcellular Localizations

Cytoplasm. Nucleus. Nucleus speckle. Colocalizes with SRSF1 in nuclear speckles.

Diseases

Myopathy
Osteitis Deformans
Neoplasms
Inclusion Body Myositis (disorder)
Frontotemporal Dementia
Dementia
Bone Diseases
Muscular Dystrophies, Limb-girdle

Dystrophy
Muscular Dystrophy
Plant Diseases

Interacting Proteins

IK
MRFAP1L1

Pathways

Mating
Cell Cycle
Virulence
Filamentous Growth
Pathogenesis
Response To Pheromone
Colony Morphology
G2 Phase
M Phase
Localization
Chromosome Segregation

Cell Cycle Arrest
Cytokinesis
Dna Replication
Mapk Cascade
Rna Interference
Spindle Assembly

PTMs

Acetylation

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SMU1

References

PMID: 15878348 by Sugaya K., et al. A temperature-sensitive mutation in the WD repeat-containing protein Smu1 is related to maintenance of chromosome integrity.

PMID: 22365833 by Hegele A., et al. Dynamic protein-protein interaction wiring of the human spliceosome.