RUFY1 Antibodies

AND RUFY1 ELISA kits, RUFY1 Proteins

Many biological assays use antibodies to detect RUFY1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RUFY1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RUFY1 antibodies...

We validate the specificity of these antibodies to RUFY1 by testing them on tissues known to express RUFY1 positively and negatively. Browse below to find the RUFY1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RUFY1 Infographic by Boster Bio

All RUFY1 Products

Product

Figures

Specificity

Applications

Price

Anti-RUFY1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A10201
100ul

RUFY1 (NM_001040451) Human Recombinant Protein

$1249
Cat # PROTQ96T51
20 µg

RUFY1 (NM_025158) Human Over-expression Lysate

Human

$960
Cat # LS080230
100 µg

Anti-RUFY1 Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A10201-1
100 µg/vial

RUFY1 Overview

Facts about RUN and FYVE domain-containing protein 1.

RUFY1 3D structure. Source: alphafold

RUN and FYVE domain-containing protein 1 (RUFY1)

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. .

Gene Information

Human
Gene Name:	RUFY1
Uniprot:	Q96T51
Entrez:	80230

Family

Belongs to:

No superfamily

Alternative Names

La-binding protein 1; Rab4-interacting protein; RABIP4FYVE-finger protein EIP1; RUN and FYVE domain containing 1; RUN and FYVE domain-containing 1; RUN and FYVE domain-containing protein 1; ZFYVE12FLJ22251; Zinc finger FYVE domain-containing protein 12

Molecular Weight

Mass (kDA):
79.818 kDA

Genomic Context


Human

Location:	5q35.3
Sequence:	5; NC_000005.10 (179550551..179610012)

Tissue Specificity

Broadly expressed, with highest levels in lung, testis, kidney and brain.

Subcellular Localizations

Cytoplasm. Early endosome membrane; Peripheral membrane protein.

Diseases

Tissue Adhesions
Multiple Acyl Coenzyme A Dehydrogenase Deficiency

Interacting Proteins

DIEXF
PIAS2
RAB39B
RAB3IP
TXNDC17

Pathways

Endocytosis
Localization
Transport
Cell Adhesion
Cell Migration
Lipid Binding

Regulation Of Endocytosis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RUFY1

References

PMID: 14617813 by Fouraux M.A., et al. Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes.

PMID: 11877430 by Yang J., et al. Interaction between tyrosine kinase Etk and a RUN-domain and FYVE- domain containing protein RUFY1. A possible role of Etk in regulation of vesicle trafficking.