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RHOT1 Antibodies
AND RHOT1 ELISA kits, RHOT1 Proteins
Many biological assays use antibodies to detect RHOT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RHOT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RHOT1 antibodies...
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RHOT1 Infographic by Boster Bio
All RHOT1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$449
Cat # A05928
0.1 mg
Cat # A05928
0.1 mg
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A05928-1
100 μg/vial
Cat # A05928-1
100 μg/vial
RHOT1 Overview
Facts about Mitochondrial Rho GTPase 1.
Mitochondrial Rho GTPase 1 (RHOT1)
Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | RHOT1 |
| Uniprot: | Q8IXI2 |
| Entrez: | 55288 |
Family
| Belongs to: |
|---|
| mitochondrial Rho GTPase family |
Alternative Names
ARHT1; EC 3.6.5; EC 3.6.5.-; FLJ11040; FLJ12633; hMiro-1; Miro1; MIRO-1mitochondrial Rho GTPase 1; mitochondrial Rho 1; rac-GTP binding protein-like protein; Rac-GTP-binding protein-like protein; Ras homolog gene family member T1; ras homolog gene family, member T1; Rhot1
Molecular Weight
Mass (kDA):
70.784 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q11.2 |
| Sequence: | 17; NC_000017.11 (32142454..32253374) |
Tissue Specificity
Ubiquitously expressed. Expressed at high level in heart and skeletal muscle.
Subcellular Localizations
Mitochondrion outer membrane; Single-pass type IV membrane protein. Colocalizes with MGARP and RHOT2 at the mitochondria.
Diseases
- Neurodegenerative Disorders
- Parkinson Disease
- Cell Invasion
- Optic Atrophy
- Mycobacterium Marinum Infection
- Sclerosis
- Neoplasm Metastasis
- Primary Lateral Sclerosis
- Hereditary Diseases
- Charcot-marie-tooth Disease
- Metastatic Malignant Neoplasm To The Lymph Node
- Neurofibromatosis 1
- Atrophy
Interacting Proteins
- KIF5C
- Kif5c
- PINK1
- PRKN
- TRAK1
Pathways
- Transport
- Mitochondrial Transport
- Mitochondrial Fusion
- Intracellular Transport
- Microtubule-based Transport
PTMs
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHOT1
bosterbio.com/bosterbio-gene-info-cards/RHOT1
References
PMID: 12696059 by Jenne D.E., et al. Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse.
PMID: 12482879 by Fransson A., et al. Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis.