PPP4R3A Antibodies

AND PPP4R3A ELISA kits, PPP4R3A Proteins

Many biological assays use antibodies to detect PPP4R3A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP4R3A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP4R3A antibodies...

We validate the specificity of these antibodies to PPP4R3A by testing them on tissues known to express PPP4R3A positively and negatively. Browse below to find the PPP4R3A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP4R3A Infographic by Boster Bio

All PPP4R3A Products

Product

Figures

Specificity

Applications

Price

Anti-SMEK1 PPP4R3A Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A12450
100ul

PPP4R3A Overview

Facts about Serine/threonine-protein phosphatase 4 regulatory subunit 3A.

PPP4R3A 3D structure. Source: alphafold

Serine/threonine-protein phosphatase 4 regulatory subunit 3A (PPP4R3A)

Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers.

The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. .

Gene Information

Human
Gene Name:	PPP4R3A
Uniprot:	Q6IN85
Entrez:	55671

Family

Belongs to:

SMEK family

Alternative Names

Serine/threonine-protein phosphatase 4 regulatory subunit 3A

Molecular Weight

Mass (kDA):
95.368 kDA

Genomic Context


Human

Location:	14q32.12
Sequence:	14; NC_000014.9 (91457137..91510554, complement)

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. In interphase localized in the cytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions.

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP4R3A

References

PMID: 16085932 by Gingras A.-C., et al. A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.

PMID: 18487071 by Martin-Granados C., et al. Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases.