Zinc transporter 6 Antibodies

AND SLC30A6 ELISA kits, Zinc transporter 6 Proteins

Many biological assays use antibodies to detect Zinc transporter 6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc transporter 6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc transporter 6 antibodies...

We validate the specificity of these antibodies to Zinc transporter 6 by testing them on tissues known to express SLC30A6 positively and negatively. Browse below to find the SLC30A6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC30A6 Infographic by Boster Bio

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Anti-Zinc transporter 6 SLC30A6 Antibody

Human, Mouse, Rat

$405
Cat # A09137
100ul

SLC30A6 Overview

Facts about Zinc transporter 6.

SLC30A6 3D structure. Source: alphafold

Zinc transporter 6 (SLC30A6)

Zinc-efflux transporter which divides the cytoplasmic zinc to the trans-Golgi network (TGN) in addition to the vesicular compartment. .

Gene Information

Human
Gene Name:	SLC30A6
Uniprot:	Q6NXT4
Entrez:	55676

Family

Belongs to:

cation diffusion facilitator (CDF) transporter (TC 2.A.4) family

Alternative Names

MGC45055; MST103; MSTP103; solute carrier family 30 (zinc transporter), member 6; Solute carrier family 30 member 6; zinc transporter 6; znT-6; ZNT6FLJ31101

Molecular Weight

Mass (kDA):
51.116 kDA

Genomic Context


Human

Location:	2p22.3
Sequence:	2; NC_000002.12 (32165841..32224379)

Tissue Specificity

Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B-cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis.

Subcellular Localizations

Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Found in vesicles.

Diseases

Alzheimer's Disease
Postmortem Changes
Impaired Cognition
Mild Cognitive Disorder
Neurofibrillary Tangles
Muscle Spasticity
Weakness
Dementia
Spastic Paraplegia, Hereditary
Cognition Disorders
Endometrial Polyp
Endoplasmic Reticulum Stress

Paraplegia
Spastic Paraplegia
Zinc Deficiency Disorder
Dental Plaque
Autoimmune Lymphoproliferative Syndrome
Chimera Disorder
Spastic Paraplegia 10, Autosomal Dominant

Pathways

Transport
Pathogenesis
Secretory Pathway
Cell Death
Localization

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC30A6

References

PMID: 15154973 by Seve M., et al. In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression.

PMID: 16580781 by Smith J.L., et al. Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain.