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- Table of Contents
Facts about p53 apoptosis effector related to PMP-22.
Plays a role as an effector in the TP53-dependent apoptotic pathway. .
Mouse | |
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Gene Name: | Perp |
Uniprot: | Q9JK95 |
Entrez: | 64058 |
Belongs to: |
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TMEM47 family |
dJ496H19.1; KCP1KCP-1; Keratinocyte-associated protein 1; KRTCAP11110017A08Rik; p53 apoptosis effector related to PMP22; p53 apoptosis effector related to PMP-22; P53-induced protein PIGPC1; PERP, TP53 apoptosis effector; PIGPC1RP3-496H19.1; THWkeratinocytes associated protein 1; Transmembrane protein THW
Mass (kDA):
21.567 kDA
Mouse | |
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Location: | 10|10 A3 |
Sequence: | 10; |
Expressed in the stratified squamous skin epithelium of the skin and the tongue, but not in simple epithelia (at protein level). Expressed in apoptotic cells.
PMID: 10733530 by Attardi L.D., et al. PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family.
PMID: 15797384 by Ihrie R.A., et al. Perp is a p63-regulated gene essential for epithelial integrity.