This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about RNA polymerase II-associated factor 1 homolog.
PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL.
Human | |
---|---|
Gene Name: | PAF1 |
Uniprot: | Q8N7H5 |
Entrez: | 54623 |
Belongs to: |
---|
PAF1 family |
F23149_1; FLJ11123; Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae); Pancreatic differentiation protein 2; PD2hPAF1; RNA polymerase II-associated factor 1 homolog
Mass (kDA):
59.976 kDA
Human | |
---|---|
Location: | 19q13.2 |
Sequence: | 19; NC_000019.10 (39385629..39391106, complement) |
Nucleus. Punctuate distribution throughout the nucleus except in nucleoli and the perinuclear chromatin.
In this article, we'll explore how Boster Bio's primary-secondary-ABC system can help you find proteins of interest. We'll also explore the Super Vision Detection Kit, which aids researchers in locating proteins that have a low background and high specificity. Download this guide to optimize your research. You'll be well on the path to developing new more efficient research methods after reading this guide.
A primary-secondary-ABC system provides researchers with the ability to easily identify proteins of interest. This unique system is based on an innovative design that allows researchers to identify proteins of interest in samples by using their existing proteomics workflow. It's also extremely versatile that allows researchers to conduct multiple experiments using a single instrument. Using this system researchers can rapidly determine the locations of proteins and make use of them as indicators for future experiments.
Primary-secondary-ABC systems allow researchers to quickly and accurately detect a wide variety of proteins, including small drugs, metabolites, and proteins. Boster Bio also produces fluorescent probes, antibodies and peptides. Its extensive line of products includes ELISA kit, antibodies, recombinant protein and recombinant proteins. In addition to these, it also offers products for immunohistochemistry, immunocytochemistry, genetics, and cancer research.
The Boster Bio primary-secondary-ABC system is an excellent way to locate proteins of interest in complex biological systems. Its kits cover a variety of biological systems and species, and are used to determine proteins of interest. These ELISA kits also allow for the measurement of biological processes like signal transduction , CD and adhesion molecules. They can also monitor metabolism, enzyme & kinase and cytokine.
A primary-secondary-ABC system is a simple way to detect a protein of interest using avidins conjugated with a signal molecule. This method has a low background and high specificity, which makes it an ideal option for a variety of applications. Other detection systems use organic or polysaccharides. Boster Bio's Super Vision detection kit is an example of a biosensor that is innovative in technology.
The creation of a point-of-care diagnostic test can be an easy and quick method to test a large number of people in just a few minutes. These kits can be used at home or at an established point-of-care in order to monitor and manage outbreaks of disease. The new test is quick and can detect SARS-CoV-2 within 30 minutes.
The detection assays for SARS-CoV-2 are examined by whole-genome sequence data. Additionally, Vogels CBF studied the effectiveness of these kits detecting SARS-CoV-2. While there aren't commercially available antibodies for this condition they could be helpful in identifying potential drugs to treat SARS. They collaborated with Dr. Donald Kohn, a distinguished professor of pediatrics and leader of several CIRM-funded clinical trials.
This technology has the potential to become an extremely fast COVID-19 diagnostic test. The technique uses reverse transcription (RT) to convert viral RNA into complementary DNA. Unlike polymerase chain reaction, RT-LAMP DNA amplification is performed in one temperature. Its high specificity makes it simple to analyze the results and doesn't require complicated laboratory equipment.
Scientists can also use the SuperVision detection kit to identify folding of proteins. It functions in the same way as the Super Vision Detection Kit but focuses on the local clusters of amino acids. The algorithm concentrates on the amino acids and analyzes their connections. It also understands that pairs of amino acids have evolved over time, limiting their potential positions within the protein. Then, it runs multiple iterations on all strings of protein, resulting in clouds of points.
This breakthrough could change the nature of vaccinology. With over eight billion people waiting for an COVID vaccine, the Baker lab was looking to develop a vaccine using a unique method. Scientists had previously relied upon surface spike proteins to defend against the deadly COVID virus. The Baker lab's approach to COVID could change this.
Human Paf1 gene is a homolog of paf1 protein. This gene is involved in pancreatic differentiation and is linked with tumorigenesis. There are many markers that are available for this gene. Boster Bio's PAF1 marker is a very specific marker that can be used to identify the human Paf1 gene. The development of tumors is also associated with pancreatic differentiation 2.
PMID: 16491129 by Moniaux N., et al. The human homologue of the RNA polymerase II-associated factor 1 (hPaf1), localized on the 19q13 amplicon, is associated with tumorigenesis.
PMID: 16024656 by Zhu B., et al. The human PAF complex coordinates transcription with events downstream of RNA synthesis.