PARP14 Antibodies

AND PARP14 ELISA kits, PARP14 Proteins

Many biological assays use antibodies to detect PARP14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PARP14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PARP14 antibodies...

We validate the specificity of these antibodies to PARP14 by testing them on tissues known to express PARP14 positively and negatively. Browse below to find the PARP14 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PARP14 Infographic by Boster Bio

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Anti-PAR14 PARP14 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A06171
100ul

PARP14 Overview

Facts about Protein mono-ADP-ribosyltransferase PARP14.

PARP14 3D structure. Source: alphafold

Protein mono-ADP-ribosyltransferase PARP14 (PARP14)

ADP-ribosyltransferase (PubMed:16061477, PubMed:27796300).
By mono-ADP-ribosylating STAT1 in'Glu-657' and'Glu-705' and consequently decreasing STAT1 phosphorylation, negatively modulates pro-inflammatory cytokines production in macrophages in response to IFNG stimulation (PubMed:27796300).

Mono-ADP- ribosylates STAT6 (By similarity). Enhances STAT6-dependent transcription (By similarity).

Gene Information

Human
Gene Name:	PARP14
Uniprot:	Q460N5
Entrez:	54625

Family

Belongs to:

No superfamily

Alternative Names

BAL2; KIAA1268; poly (ADP-ribose) polymerase family, member 14

Molecular Weight

Mass (kDA):
202.8 kDA

Genomic Context


Human

Location:	3q21.1
Sequence:	3; NC_000003.12 (122680726..122730840)

Tissue Specificity

Expressed in macrophages.

Subcellular Localizations

Nucleus. Cytoplasm. In steady state splenocytes the protein is mostly nuclear (By similarity). A minor proportion is detected in the cytoplasm (By similarity). In macrophages, mainly localizes to the cytoplasm (PubMed:27796300).

Diseases

Malignant Neoplasms
Cell Transformation, Neoplastic
Leukemogenesis
Lymphoma
Inflammation
Diphtheria

Aggressive Non-hodgkin Lymphoma

Pathways

Dna Repair
Immune Response
Glycolysis
Oncogenesis

PTMs

Ribosylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PARP14

References

PMID: 16344560 by Kimura K., et al. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.

PMID: 16061477 by Aguiar R.C.T., et al. B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity.