OTUB1 Antibodies

AND OTUB1 ELISA kits, OTUB1 Proteins

Many biological assays use antibodies to detect OTUB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OTUB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OTUB1 antibodies...

We validate the specificity of these antibodies to OTUB1 by testing them on tissues known to express OTUB1 positively and negatively. Browse below to find the OTUB1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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OTUB1 Infographic by Boster Bio

All OTUB1 Products

Product

Figures

Specificity

Applications

Price

Anti-Ubiquitin thioesterase OTUB1 OTUB1 Antibody

Human, Mouse, Rat

$405
Cat # A04361
100ul

Human Otubain-1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ96FW1
Starting from 20ug

Anti-OTUB1 Mouse Monoclonal Antibody [Clone ID: OTI5B8]

+10

Human, Rat

Flow Cytometry, IHC, WB

$523
Cat # M04361
100 µl

Anti-OTUB1 Mouse Monoclonal Antibody [Clone ID: OTI2H1]

Human, Rat

IF, IHC, WB

$523
Cat # M04361-1
100 µl

OTUB1 (NM_017670) Human Over-expression Lysate

Human

$628
Cat # LS055611
100 µg

Anti-OTUB1 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A04361-1
100 µg/vial

OTUB1 Overview

Facts about Ubiquitin thioesterase OTUB1.

OTUB1 3D structure. Source: alphafold

Ubiquitin thioesterase OTUB1 (OTUB1)

Hydrolase that can specifically remove'Lys-48'-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen.

Acts through its interaction with RNF128/GRAIL, a crucial inductor of CD4 T-cell anergy. Isoform 1 destabilizes RNF128, leading to prevent anergy.

Gene Information

Human
Gene Name:	OTUB1
Uniprot:	Q96FW1
Entrez:	55611

Family

Belongs to:

peptidase C65 family

Alternative Names

Deubiquitinating enzyme OTUB1; EC 3.1.2; EC 3.4.19.12; FLJ20113; FLJ40710; hOTU1; MGC111158; OTB1; OTB1MGC4584; OTU domain, ubiquitin aldehyde binding 1; OTU domain-containing ubiquitin aldehyde-binding protein 1; OTU1; OTU1OTU-domain Ubal-binding 1; OTUB1; Otubain1; Otubain-1; ubiquitin thioesterase OTUB1; ubiquitin-specific protease otubain 1; Ubiquitin-specific-processing protease OTUB1

Molecular Weight

Mass (kDA):
31.284 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (63985853..63998420)

Tissue Specificity

Isoform 1 is ubiquitous. Isoform 2 is expressed only in lymphoid tissues such as tonsils, lymph nodes and spleen, as well as peripheral blood mononuclear cells.