NF-kappa-B inhibitor delta (NFKBID)

Regulates the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory reactions.

Involved in the induction of T helper 17 cells (Th17) distinction upon recognition of antigen by T cell antigen receptor (TCR). May also regulate TCR-induced negative selection of thymocytes.