MMP28 Antibodies

Matrix metalloproteinase-28 (MMP28)

Can degrade casein. Could play a role in tissues homeostasis and repair.

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Gene Information

Human
Gene Name:	MMP28
Uniprot:	Q9H239
Entrez:	79148

Family

Belongs to:
peptidase M10A family

Alternative Names

EC 3.4.24; EC 3.4.24.-; Epilysin; matrix metallopeptidase 28; matrix metalloproteinase 28; MM28; MMP25; MMP28; MMP-28; MMP-28MMP-25; putative MMP28 gene product

Molecular Weight

Mass (kDA):
58.939 kDA

Genomic Context

Human
Location:	17q12
Sequence:	17; NC_000017.11 (35756249..35795707, complement)

Tissue Specificity

Expressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fetal lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytes. Widely expressed in several carcinomas as well. Is up-regulated in response to injury in the skin.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

• Carcinoma
• Malignant Neoplasms
• Neoplasms
• Cell Invasion
• Degenerative Polyarthritis
• Nervousness
• Neoplasm Metastasis
• Ulcer
• Malignant Paraganglionic Neoplasm
• Inflammation
• Tissue Adhesions
• Inflammatory Bowel Diseases

• Neoplasm Invasiveness
• Intestinal Diseases
• Pathologic Neovascularization
• Osteoarthritis Of Hip
• Intervertebral Disc Degeneration
• Malignant Neoplasm Of Lung

Interacting Proteins

• FURIN

Pathways

• Wound Healing
• Localization
• Tissue Homeostasis
• Epithelial To Mesenchymal Transition
• Cell Migration
• Proteolysis
• Myelination
• Reverse Transcription
• Secretion
• Cell Adhesion
• Cell Proliferation
• Aging
• Protein Secretion

• Limb Development
• Regeneration
• Chemotaxis
• Translation
• Embryo Implantation
• Cell Motility
• Cellular Localization

PTMs

• Cleavage

• Phosphorylation

• Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MMP28

Boster Bio Review - Best Uses Of The MMP28 Marker

This article will focus on Boster Bio as well as the MMP28 Marker. You'll also learn about Boster Bio’s Macrophage Marker, and Macrophage Apoptosis Detection Kit. The Boster Bio Anti-CD68 Macrophage Marker Monoclonal Antibody is non-hazardous and can be purchased without BSA. The price of the antibody includes a blocking peptide, which can be added on depending on the immunogen's length.

Boster Bio

MMP28 is a major component of keratinocytes, which break down collagen fibers and other matrix proteins. MMP28 expression is also seen in skin cancers. However, we are still not sure what this protein does. Boster Bio's MMP28 antibody has been used in numerous studies to confirm the protein's presence in different cancer samples. Visit the company's website for more information about the MMP28 marker.

Macrophage Marker

MMP28 is a common protein that is found in animal and human tissues. Boster Bio supplies monoclonal antibodies to detect this protein for a variety of applications including IHC. These monoclonal antibodies are non-hazardous. Alternatively, blocking peptide can be purchased at 1.0 mg/ml. The costs for blocking peptides vary depending on the immunogen length.

MMP28

MMP28 is a protein that has a variety of effects on human cells, including skin tissue and heart tissue. This protein is found within keratinocytes. It is also up-regulated in tissue injury. Boster Bio’s MMP28 monoclonal Antibody reacts to MMP28 in a wide range samples, including human tissue and skin. The MMP28 marker is a versatile tool that can be used in a variety fields, including clinical diagnostics.

Macrophage apoptosis detection kit

This Boster Bio Macrophage aPoptosis detection kit enables researchers to measure the activity of caspases, a family of cysteine proteases that respond in succession to various apoptotic stimuli. Pro-apoptotic stimuli are tumor necrosis factor, growth factor receptor-bound proteins (FasL), DNA damages, and calcium channels.