Fatty acid 2-hydroxylase Antibodies

AND FA2H ELISA kits, Fatty acid 2-hydroxylase Proteins

Many biological assays use antibodies to detect Fatty acid 2-hydroxylase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fatty acid 2-hydroxylase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fatty acid 2-hydroxylase antibodies...

We validate the specificity of these antibodies to Fatty acid 2-hydroxylase by testing them on tissues known to express FA2H positively and negatively. Browse below to find the FA2H antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FA2H Infographic by Boster Bio

All FA2H Products

Product

Figures

Specificity

Applications

Price

Anti-Fatty acid 2-hydroxylase FA2H Antibody

Human, Rat

$405
Cat # A05657
100ul

Anti-Fatty acid 2-hydroxylase FA2H Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05657-1
100ul

FA2H (NM_024306) Human Recombinant Protein

$1249
Cat # PROTQ7L5A8
20 µg

Anti-FA2H Mouse Monoclonal Antibody [Clone ID: OTI2E3]

Human

IF, WB

$523
Cat # M05657
100 µl

FA2H (NM_024306) Human Over-expression Lysate

Human

$628
Cat # LS079152
100 µg

FA2H Overview

Facts about Fatty acid 2-hydroxylase.

FA2H 3D structure. Source: alphafold

Fatty acid 2-hydroxylase (FA2H)

Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids. .

Gene Information

Human
Gene Name:	FA2H
Uniprot:	Q7L5A8
Entrez:	79152

Family

Belongs to:

sterol desaturase family

Alternative Names

FAAHFAXDC1; FAH1; fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; fatty acid hydroxylase domain containing 1; FLJ25287; SCS7; spastic paraplegia 35 (autosomal recessive); SPG35

Molecular Weight

Mass (kDA):
42.791 kDA

Genomic Context


Human

Location:	16q23.1
Sequence:	16; NC_000016.10 (74712955..74774831, complement)

Tissue Specificity

Detected in differentiating cultured keratinocytes (at protein level). Detected in epidermis and cultured keratinocytes. Highly expressed in brain and colon. Detected at lower levels in testis, prostate, pancreas and kidney.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.

Diseases

Neurodegenerative Disorders
Nerve Degeneration
Leukodystrophy
Paraplegia
Nervousness
Spastic Paraplegia
Paraparesis
Paraparesis, Spastic
Impaired Cognition
Spastic Paraplegia, Hereditary
Dystonia Disorders
Atrophy

Muscle Spasticity
Ataxia
Malignant Neoplasms
Neoplasms
Globus Hystericus
Neurilemmoma

Pathways

Myelination
Fatty Acid Alpha-oxidation
Pathogenesis
Hair Follicle Morphogenesis
Nadph Regeneration
Fatty Acid Elongation
Keratinocyte Differentiation
Regeneration
Schwann Cell Differentiation
Myelin Maintenance
Cell Death
Cell Cycle

Cell Differentiation
Anagen
Mapk Cascade
Telogen
Rna Interference
Oligodendrocyte Differentiation

PTMs

Hydroxylation

Oxidation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FA2H

References

PMID: 15337768 by Alderson N.L., et al. The human FA2H gene encodes a fatty acid 2-hydroxylase.

PMID: 15863841 by Alderson N.L., et al. A novel method for the measurement of in vitro fatty acid 2- hydroxylase activity by gas chromatography-mass spectrometry.