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- Table of Contents
Facts about Fatty acid 2-hydroxylase.
Human | |
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Gene Name: | FA2H |
Uniprot: | Q7L5A8 |
Entrez: | 79152 |
Belongs to: |
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sterol desaturase family |
FAAHFAXDC1; FAH1; fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; fatty acid hydroxylase domain containing 1; FLJ25287; SCS7; spastic paraplegia 35 (autosomal recessive); SPG35
Mass (kDA):
42.791 kDA
Human | |
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Location: | 16q23.1 |
Sequence: | 16; NC_000016.10 (74712955..74774831, complement) |
Detected in differentiating cultured keratinocytes (at protein level). Detected in epidermis and cultured keratinocytes. Highly expressed in brain and colon. Detected at lower levels in testis, prostate, pancreas and kidney.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
PMID: 15337768 by Alderson N.L., et al. The human FA2H gene encodes a fatty acid 2-hydroxylase.
PMID: 15863841 by Alderson N.L., et al. A novel method for the measurement of in vitro fatty acid 2- hydroxylase activity by gas chromatography-mass spectrometry.