KIZ Antibodies

AND KIZ ELISA kits, KIZ Proteins

Many biological assays use antibodies to detect KIZ, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIZ in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIZ antibodies...

We validate the specificity of these antibodies to KIZ by testing them on tissues known to express KIZ positively and negatively. Browse below to find the KIZ antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KIZ Infographic by Boster Bio

All KIZ Products

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Product

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Specificity

Applications

Price

Anti-Centrosomal protein kizuna KIZ Antibody

Human

ELISA, WB

$380
Cat # A04420
100ul

C20orf19 (KIZ) (NM_018474) Human Over-expression Lysate

Human

$628
Cat # LS055857
100 µg

KIZ Overview

Facts about Centrosomal protein kizuna.

KIZ 3D structure. Source: alphafold

Centrosomal protein kizuna (KIZ)

Centrosomal protein needed for establishing a robust mitotic centrosome structure that could endure the forces that converge to the centrosomes during spindle formation. Required for stabilizing the enlarged pericentriolar material around the centriole.

Gene Information

Human
Gene Name:	KIZ
Uniprot:	Q2M2Z5
Entrez:	55857

Family

Belongs to:

kizuna family

Alternative Names

Centrosomal protein kizuna

Molecular Weight

Mass (kDA):
75.111 kDA

Genomic Context


Human

Location:	20p11.23
Sequence:	20; NC_000020.11 (21125975..21246622)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Localizes to centrosomes throughout the cell cycle. After centrosome duplication, it usually remains associated only with the mother centrosome, containing the older mature centriole and particles surrounding it. During prophase, additional particles accumulate around both separating centrosomes. Does not accumulate at the microtubule minus ends, but instead localizes to the centrosomes and centrosome-surrounding area in a microtubule-independent and dependent manner, respectively.

Diseases

Retinitis pigmentosa 69 (RP69)

Interacting Proteins

CEP72
MEOX2
TACC3

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIZ

References

PMID: 16980960 by Oshimori N., et al. The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity.

PMID: 19536135 by Oshimori N., et al. Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation.