Junctophilin-4 Antibodies

AND JPH4 ELISA kits, Junctophilin-4 Proteins

Many biological assays use antibodies to detect Junctophilin-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Junctophilin-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Junctophilin-4 antibodies...

We validate the specificity of these antibodies to Junctophilin-4 by testing them on tissues known to express JPH4 positively and negatively. Browse below to find the JPH4 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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JPH4 Infographic by Boster Bio

All JPH4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-JPH2 JPH4 Antibody

Human, Mouse, Rat

ELISA, WB

$449
Cat # A13608
0.1 mg

Anti-Junctophilin-4 JPH4 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A13608-1
0.1 mg

JPH4 (NM_032452) Human Recombinant Protein

$813
Cat # PROTQ96JJ6
20 µg

JPH4 (NM_032452) Human Over-expression Lysate

Human

$628
Cat # LS084502
100 µg

JPH4 Overview

Facts about Junctophilin-4.

JPH4 3D structure. Source: alphafold

Junctophilin-4 (JPH4)

Junctophilins contribute to the formation of junctional membrane complexes (JMCs) that link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.

JPH4 is brain- specific and appears to have an active part in certain neurons involved in motor coordination and memory (By similarity). .

Gene Information

Human
Gene Name:	JPH4
Uniprot:	Q96JJ6
Entrez:	84502

Family

Belongs to:

junctophilin family

Alternative Names

JP4; JP-4; JPHL1; Junctophilin 4; Junctophilin Like 1; junctophilin-4; Junctophilin-Like 1 Protein; KIAA1831

Molecular Weight

Mass (kDA):
65.861 kDA

Genomic Context


Human

Location:	14q11.2
Sequence:	14; NC_000014.9 (23568038..23578790, complement)

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity).

Diseases

Carcinoma, Endometrioid
Cell Invasion
Learning Disorders
Adenocarcinoma
Cell Transformation, Neoplastic
Tumor Progression
Endometrial Adenocarcinoma
Endometrial Neoplasms
Endometrial Polyp
Memory Disorders

Malignant Neoplasms
Neoplasms
Memory Impairment
Endometrial Carcinoma

Pathways

Localization
Reflex

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/JPH4

References

PMID: 11347906 by Nagase T., et al. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PMID: 17974005 by Bechtel S., et al. The full-ORF clone resource of the German cDNA consortium.