INTS5 Antibodies

AND INTS5 ELISA kits, INTS5 Proteins

Many biological assays use antibodies to detect INTS5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with INTS5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop INTS5 antibodies...

We validate the specificity of these antibodies to INTS5 by testing them on tissues known to express INTS5 positively and negatively. Browse below to find the INTS5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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INTS5 Infographic by Boster Bio

All INTS5 Products

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Specificity

Applications

Price

Anti-Integrator complex subunit 5 INTS5 Antibody

Human, Mouse

IHC, WB

$405
Cat # A14452
100ul

INTS5 (NM_030628) Human Over-expression Lysate

Human

$628
Cat # LS080789
100 µg

INTS5 Overview

Facts about Integrator complex subunit 5.

INTS5 3D structure. Source: alphafold

Integrator complex subunit 5 (INTS5)

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable).

Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). .

Gene Information

Human
Gene Name:	INTS5
Uniprot:	Q6P9B9
Entrez:	80789

Family

Belongs to:

Integrator subunit 5 family

Alternative Names

Int5; integrator complex subunit 5; KIAA1698INT5

Molecular Weight

Mass (kDA):
107.995 kDA

Genomic Context


Human

Location:	11q12.3
Sequence:	11; NC_000011.10 (62646848..62653302, complement)

Subcellular Localizations

Nucleus membrane; Multi-pass membrane protein. Nucleus. Cytoplasm.

Diseases

Acute Undifferentiated Leukemia
Leukemia

Pathways

Snrna Processing
Cell Development
Cell Differentiation
Rna Processing
Rna Splicing

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INTS5

References

PMID: 16239144 by Baillat D., et al. Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.

PMID: 23904267 by Jodoin J.N., et al. Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.