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- Table of Contents
Facts about Interferon alpha-inducible protein 6.
Has an antiviral action towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells (PubMed:25757571). .
Human | |
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Gene Name: | IFI6 |
Uniprot: | P09912 |
Entrez: | 2537 |
Belongs to: |
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IFI6/IFI27 family |
Interferon alpha-inducible protein 6
Mass (kDA):
12.927 kDA
Human | |
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Location: | 1p35.3 |
Sequence: | 1; NC_000001.11 (27666061..27672229, complement) |
Mitochondrion inner membrane; Multi-pass membrane protein.
PMID: 3017706 by Kelly J.M., et al. Characterization of a human gene inducible by alpha- and beta- interferons and its expression in mouse cells.
PMID: 7596809 by Turri M.G., et al. Characterisation of a novel minisatellite that provides multiple splice donor sites in an interferon-induced transcript.