SLC37A4 Antibodies

AND SLC37A4 ELISA kits, SLC37A4 Proteins

Many biological assays use antibodies to detect SLC37A4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC37A4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC37A4 antibodies...

We validate the specificity of these antibodies to SLC37A4 by testing them on tissues known to express SLC37A4 positively and negatively. Browse below to find the SLC37A4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC37A4 Infographic by Boster Bio

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Anti-SLC37A4 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03501
100ul

SLC37A4 Overview

Facts about Glucose-6-phosphate exchanger SLC37A4.

SLC37A4 3D structure. Source: alphafold

Glucose-6-phosphate exchanger SLC37A4 (SLC37A4)

Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6- phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction.

Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Consequently, it plays a central role in homeostatic regulation of blood glucose levels.

Gene Information

Human
Gene Name:	SLC37A4
Uniprot:	O43826
Entrez:	2542

Family

Belongs to:

major facilitator superfamily

Alternative Names

G6PT; G6PT1G6PT3; G6PT2; Glucose-5-phosphate transporter; glucose-6-phosphatase, transport (glucose) protein 3; glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1; glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2; glucose-6-phosphate translocase; GSD1b; GSD1c; GSD1d; MGC15729; microsomal glucose-6-phosphate transporter; solute carrier family 37 (glucose-6-phosphate transporter), member 4; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG19; TRG-19

Molecular Weight

Mass (kDA):
46.36 kDA

Genomic Context


Human

Location:	11q23.3
Sequence:	11; NC_000011.10 (119024112..119030906, complement)

Tissue Specificity

Mostly expressed in liver and kidney.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Glycogen Storage Disease
Storage Disease
Glycogen Storage Disease Type I
Glucose-6-phosphate Transport Defect
Hypoglycemia
Diabetes Mellitus
Hepatomegaly
Infective Disorder
Diabetes Mellitus, Non-insulin-dependent
Qualitative Abnormality Of Granulocyte
Neoplasms
Liver Carcinoma
Inborn Errors Of Metabolism

Metabolic Diseases
Intestinal Diseases
Inflammatory Bowel Diseases
Hyperlipidemia
Brain Neoplasms
Neutropenia Chronic
Dwarfism

Pathways

Transport
Glucose Homeostasis
Gluconeogenesis
Glucose-6-phosphate Transport
Secretion
Chemotaxis
Insulin Secretion
Gene Silencing
Glucose Transport
Cell Death
Pathogenesis
Neutrophil Differentiation
Heteroduplex Formation

Translation
Respiratory Burst
Regulation Of Insulin Secretion
Glycolysis
Programmed Cell Death
Cell Cycle Phase
Cellular Homeostasis

PTMs

Phosphorylation
Glycosylation

Cleavage
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC37A4

References

PMID: 9428641 by Gerin I., et al. Sequence of a putative glucose 6-phosphate translocase, mutated in glycogen storage disease type Ib.

PMID: 9856496 by Ihara K., et al. Genomic structure of the human glucose 6-phosphate translocase gene and novel mutations in the gene of a Japanese patient with glycogen storage disease type Ib.