GSAP Antibodies

AND GSAP ELISA kits, GSAP Proteins

Many biological assays use antibodies to detect GSAP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GSAP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GSAP antibodies...

We validate the specificity of these antibodies to GSAP by testing them on tissues known to express GSAP positively and negatively. Browse below to find the GSAP antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GSAP Infographic by Boster Bio

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GSAP Overview

Facts about Gamma-secretase-activating protein.

GSAP 3D structure. Source: alphafold

Gamma-secretase-activating protein (GSAP)

Regulator of gamma-secretase activity, which specifically activates the creation of amyloid-beta protein (amyloid-beta protein 40 and amyloid-beta protein 42), without affecting the cleavage of additional gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein).

Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate amyloid- beta, while it reduces the epsilon-cleavage of APP CTF-alpha, causing a very low production of AICD. .