GFPT1 Antibodies

AND GFPT1 ELISA kits, GFPT1 Proteins

Many biological assays use antibodies to detect GFPT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GFPT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GFPT1 antibodies...

We validate the specificity of these antibodies to GFPT1 by testing them on tissues known to express GFPT1 positively and negatively. Browse below to find the GFPT1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GFPT1 Infographic by Boster Bio

All GFPT1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GFPT1 Antibody

Human, Mouse, Rat

$405
Cat # A04341
100ul

Human GFPT1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ06210
Starting from 20ug

Anti-GFPT1 Antibody Picoband®

Human, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04341-1
100 μg/vial

Anti-GFPT1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IHC, WB

$370
Cat # M04341
100 μl/vial

GFPT1 (NM_002056) Human Over-expression Lysate

Human

$628
Cat # LS002673
100 µg

GFPT1 Overview

Facts about Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1.

GFPT1 3D structure. Source: alphafold

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1)

Controls the level of glucose into the hexosamine pathway. Most probably involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.

Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1. .

Gene Information

Human
Gene Name:	GFPT1
Uniprot:	Q06210
Entrez:	2673

Family

Belongs to:

No superfamily

Alternative Names

glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1; CMSTA1; GFA; GFAT 1; GFAT; GFAT1; GFAT1m; GFPT; GFPT1L; glutamine--fructose-6-phosphate transaminase 1; MSLG

Molecular Weight

Mass (kDA):
78.806 kDA

Genomic Context


Human

Location:	2p13.3
Sequence:	2; NC_000002.12 (69319780..69387227, complement)

Tissue Specificity

Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Myasthenic Syndromes, Congenital
Insulin Resistance
Malignant Neoplasms
Diabetic Nephropathy
Kidney Diseases
Weakness
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Complications Of Diabetes Mellitus
Muscle Weakness

Cholangiocarcinoma
Myasthenias
Dyslipidemias
Thymoma
Malignant Neoplasm Of Lung
Parkinson Disease

Pathways

Glycosylation
Transport
Cell Proliferation
Secretion
Protein Glycosylation
Insulin Secretion
Pathogenesis
Cell Adhesion
Transposition
Neuromuscular Junction Development
Regulation Of Signaling
Muscle Contraction
Biosynthetic Process

Cell Division
Translation
Cell Cycle
Steroid Biosynthetic Process
Glucose Transport
Melanocyte Differentiation
Signal Transmission

PTMs

Glycosylation

Phosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GFPT1

References

PMID: 1460020 by McKnight G.L., et al. Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase.

PMID: 11679416 by DeHaven J.E., et al. A novel variant of glutamine:fructose-6-phosphate amidotransferase-1 (GFAT1) mRNA is selectively expressed in striated muscle.