Fidgetin-like protein 1 Antibodies

AND Fignl1 ELISA kits, Fidgetin-like protein 1 Proteins

Many biological assays use antibodies to detect Fidgetin-like protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fidgetin-like protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fidgetin-like protein 1 antibodies...

We validate the specificity of these antibodies to Fidgetin-like protein 1 by testing them on tissues known to express Fignl1 positively and negatively. Browse below to find the Fignl1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Fignl1 Infographic by Boster Bio

All Fignl1 Products

Product

Figures

Specificity

Applications

Price

Anti-Fidgetin-like protein 1 FIGNL1 Antibody

Human

$405
Cat # A11057
100ul

FIGNL1 (NM_001042762) Human Over-expression Lysate

Human

$628
Cat # LS063979
100 µg

Fignl1 Overview

Facts about Fidgetin-like protein 1.

Fidgetin-like protein 1 (Fignl1)

Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited in DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX- dependent manner.

May regulate osteoblast proliferation and differentiation (PubMed:17352653). May play a role in the management of male meiosis dynamic (PubMed:22110678).

Gene Information

Mouse
Gene Name:	Fignl1
Uniprot:	Q8BPY9
Entrez:	60530

Family

Belongs to:

AAA ATPase family

Alternative Names

EC 3.6.4; EC 3.6.4.-; fidgetin-like 1; fidgetin-like protein 1

Molecular Weight

Mass (kDA):
74.85 kDA

Genomic Context


Mouse

Location:	11\|11 A1
Sequence:	11;

Tissue Specificity

Expressed at high level in the testis (PubMed:22110678). Detected in pachytene spermatocytes and in metaphase spermatocytes (at protein level).

Diseases

Insulinoma
Aortic Aneurysm, Abdominal

Pathways

Cell Proliferation
Osteoblast Differentiation
Cell Cycle
Cell Death
Prophase
Male Meiosis
Osteoblast Proliferation

Meiosis
Spermatogenesis

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Fignl1

References

PMID: 11017077 by Cox G.A., et al. The mouse fidgetin gene defines a new role for AAA family proteins in mammalian development.

PMID: 17352653 by Park S.J., et al. Fidgetin-like 1 gene inhibited by basic fibroblast growth factor regulates the proliferation and differentiation of osteoblasts.