FGF9 Antibodies

Fibroblast growth factor 9 (FGF9)

Plays an essential role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.

.

Gene Information

Human
Gene Name:	FGF9
Uniprot:	P31371
Entrez:	2254

Family

Belongs to:
heparin-binding growth factors family

Alternative Names

FGF9; FGF-9; fibroblast growth factor 9 (glia-activating factor); Fibroblast growth factor 9; GAF; glia-activating factor; HBFG-9; HBGF-9; Heparin-binding growth factor 9; MGC119914; MGC119915; SYNS3

Molecular Weight

Mass (kDA):
23.441 kDA

Genomic Context

Human
Location:	13q12.11
Sequence:	13; NC_000013.11 (21671073..21704501)

Tissue Specificity

Glial cells.

Subcellular Localizations

Secreted.

Diseases

• Malignant Neoplasms
• Neoplasms
• Congenital Abnormality
• Hypertrophy
• Carcinoma
• Tissue Adhesions
• Cell Transformation, Neoplastic
• Endometrial Polyp
• Nervousness
• Hypoplasia
• Disorders Of Sex Development
• Adenocarcinoma
• Malignant Paraganglionic Neoplasm

• Achondroplasia
• Craniosynostosis
• Tumor Angiogenesis
• Pathologic Neovascularization
• Prostatic Neoplasms
• Glioma
• Crest Syndrome

Pathways

• Cell Proliferation
• Sex Determination
• Cell Differentiation
• Localization
• Sertoli Cell Differentiation
• Pathogenesis
• Meiosis
• Regeneration
• Lung Development
• Male Sex Determination
• Ossification
• Cell Development
• Secretion

• Cell Growth
• Angiogenesis
• Cell Adhesion
• Cell Migration
• Limb Development
• Endochondral Ossification
• Germ Cell Development

PTMs

• Phosphorylation
• Cleavage

• Glycosylation
• Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FGF9

Boster Bio: Best Uses Of The FGF9 Marker

You've come to a good spot if you're thinking about purchasing Anti-FGF9 antigens. We've previously discussed Steven Boster, the company which makes the anti-FGF9 antibodies and will discuss the way that the product functions in clinical environments. We'll also talk about how Boster's anti FGF9 antibody can aid your research.

Anti-FGF9 antibody

An antibody targeting the fibroblast growth factor 9 (FGF9) gene encodes an enzyme that belongs to the growth factors for fibroblasts. The members of this family have diverse mitogenic functions and are involved in a range of biological processes, including cell growth and morphogenesis as well as tissue repair and the growth of tumors. It has been proven that the growth of tumors can be stimulated through the overexpression of this gene. While it isn't expressed in the testes or the ovaries in adulthood, its timing of expression suggests that it could play an important role in the development of embryonic epithelial tissue.

Clinical applications

The FGF9 marker is a new protein with multiple potential clinical applications. FGF9 aids in the formation of synapses through the stimulation of neurite outgrowth and increasing synaptic proteins. FGF9 is found within the brain in various cells, including neurons, fibrocytes and glial cells. However its role in HD is still unclear. FGF9 treatment was found to increase the outgrowth of Q7 neurons and Q111 neurons in this study.

There is evidence mounting that FGF9 might have neuroprotective qualities. As the cell-cycle regulator of many neuronal tissues, FGF9 may aid in treatments for disorders that affect the central nervous system. Neurons in the brain require an adequate amount of development to function properly. In neurodegenerative diseases such as Huntington's Disease, impairment of neuronal structures leads to central nervous system dysfunction and neuronal death. FGF9 is thought to play a part in neuronal development, neurite growth, and other functions. While the effects of FGF9 on neuronal function remain unclear however, this protein could be involved in neuroprotection by its ability to alter the structure and function of neurons.

In addition to cell-cycle genes, FGF9 promotes S phase cell division. This process also increases cell numbers. This means that FGF9 can help to prevent HD disease conditions. Although the findings of the study haven't been conclusive but it is an encouraging step towards furthering the field of the field of hematology. The FGF9 marker is an essential instrument for clinical use. Although there are many advantages associated with its use, doctors must decide if it is the right treatment for HD patients.

The FGF9 gene is upregulated in mesonephroi in culture. Mesonephric cells in culture migrate into XY gonads but not into XX gonadods. The FGF9 gene induces this migration in 26 of the 31 XX Gonads. This results suggests that FGF9 regulates the Etv5 signaling pathway in mesonephric cells.

To study regeneration and repair, the sciatic nerve transsection model in rats was utilized. FGF9 stimulated a myelin sleeve and Schwann cells. By using this marker, researchers can determine if FGF9 stimulates regeneration and avoids muscular atrophy. FGF9-NLCs might hinder the regeneration of sciatic nerve.