FGF12 Antibodies

AND FGF12 ELISA kits, FGF12 Proteins

Many biological assays use antibodies to detect FGF12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FGF12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FGF12 antibodies...

We validate the specificity of these antibodies to FGF12 by testing them on tissues known to express FGF12 positively and negatively. Browse below to find the FGF12 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FGF12 Infographic by Boster Bio

All FGF12 Products

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Figures

Specificity

Applications

Price

Anti-FGF-12 Antibody

4 Q&As

Human, Mouse, Rat

IHC, WB

$399
Cat # A07326
100μl

FGF12 (NM_021032) Human Recombinant Protein

$813
Cat # PROTP61328
20 µg

FGF12 (NM_021032) Human Over-expression Lysate

Human

$628
Cat # LS002257
100 µg

Human recombinant FGF-12 (Fibroblast growth factor-12) protein, AF

Human

Cell Culture

$77
Cat # PROTP61328-2
5ug,20ug,100ug,500ug,1mg

FGF12 Overview

Facts about Fibroblast growth factor 12.

FGF12 3D structure. Source: alphafold

Fibroblast growth factor 12 (FGF12)

Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity.

Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. .

Gene Information

Human
Gene Name:	FGF12
Uniprot:	P61328
Entrez:	2257

Family

Belongs to:

heparin-binding growth factors family

Alternative Names

FGF12; FGF-12; FGF12B; FHF1; FHF-1; FHF1Fibroblast growth factor homologous factor 1; fibroblast growth factor 12; fibroblast growth factor 12B; fibroblast growth factor FGF-12b; Myocyte-activating factor

Molecular Weight

Mass (kDA):
27.399 kDA

Genomic Context


Human

Location:	3q28-q29
Sequence:	3; NC_000003.12 (192139390..192727541, complement)

Tissue Specificity

Brain, eye and testis; highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and in a segmental pattern of the body wall; in adult olfactory bulb, less in cerebellum, deep cerebellar nuclei, cortex and multiple midbrain structures.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Squamous Cell Neoplasm
Mammary Neoplasms
Esophageal Neoplasms
Cleft Palate
Squamous Cell Carcinoma Of Esophagus
Nervousness
Cytogenetic Abnormality
Cleft Lip
Aneurysm
Neoplasm Metastasis

Malignant Neoplasm Of Breast
Ataxia
Glioma
Fibrosis
Tumor Angiogenesis
Tissue Damage
Pathologic Neovascularization

Interacting Proteins

COIL
DCTD
IKZF1
LZTS2
SCN5A

ZNF460

Pathways

Methylation
Cell Growth
Pathogenesis
Thermoception
Membrane Depolarization
Cell Proliferation
Dna Methylation
Angiogenesis

Ossification
Odontogenesis
Secretion

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FGF12

References

PMID: 8790420 by Smallwood P.M., et al. Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.

PMID: 10049777 by Kok L.D.S., et al. Cloning and characterization of a cDNA encoding a novel fibroblast growth factor preferentially expressed in human heart.