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- Table of Contents
1 Citations 1 Q&As
Facts about Low affinity immunoglobulin gamma Fc region receptor II-a.
By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Human | |
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Gene Name: | FCGR2A |
Uniprot: | P12318 |
Entrez: | 2212 |
Belongs to: |
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No superfamily |
CD32 antigen; CD32a; CD32MGC23887; CDw32fc-gamma-RIIa; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc gamma RIIA; FCG2; Fc-gamma RII-a; Fc-gamma-RIIa; FcGR; FCGR2; FCGR2A; FCGR2A1; FcgRIIA; FCRIIA; fcRII-a; IGFR2MGC30032; IgG Fc receptor II-a; Immunoglobulin G Fc receptor II; low affinity immunoglobulin gamma Fc region receptor II-a
Mass (kDA):
35.001 kDA
Human | |
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Location: | 1q23.3 |
Sequence: | 1; NC_000001.11 (161505430..161524048) |
Found on monocytes, neutrophils and eosinophil platelets.
Cell membrane; Single-pass type I membrane protein.
PMID: 2824655 by Stuart S.G., et al. Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).
PMID: 2529342 by Brooks D.G., et al. Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes.
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