FCGR3B Antibodies

AND FCGR3B ELISA kits, FCGR3B Proteins

Many biological assays use antibodies to detect FCGR3B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCGR3B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCGR3B antibodies...

We validate the specificity of these antibodies to FCGR3B by testing them on tissues known to express FCGR3B positively and negatively. Browse below to find the FCGR3B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FCGR3B Infographic by Boster Bio

All FCGR3B Products

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Specificity

Applications

Price

Anti-FCGR3B Antibody

Human, Mouse, Rat

$405
Cat # A01177
100ul

Human Fc gamma RIIIB/CD16b Recombinant Protein

SDS-PAGE

$265
Cat # PROTO75015
Starting from 10ug

FCGR3B Overview

Facts about Low affinity immunoglobulin gamma Fc region receptor III-B.

FCGR3B 3D structure. Source: alphafold

Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B)

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor.

Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, isn't capable to mediate antibody-dependent cytotoxicity and phagocytosis.

Gene Information

Human
Gene Name:	FCGR3B
Uniprot:	O75015
Entrez:	2215

Family

Belongs to:

No superfamily

Alternative Names

CD16; CD16A; Fc fragment of IgG receptor IIIa; Fc gamma RIII; FCG3; FCGR3; FcgRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20

Molecular Weight

Mass (kDA):
26.216 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (161623196..161631963, complement)

Tissue Specificity

Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Secreted after cleavage.

Diseases

Lymphoma
Malignant Neoplasms
Arthritis
Rheumatoid Arthritis
Neoplasms
Lupus Erythematosus, Systemic
Autoimmune Reaction
Autoimmune Diseases
Lymphoma, Non-hodgkin
B-cell Lymphomas
Lymphoma, Follicular
Colorectal Cancer
Colorectal Neoplasms

Dysequilibrium Syndrome
Malignant Neoplasm Of Breast
Hiv Infections
Infective Disorder
Mammary Neoplasms
Diffuse Large B-cell Lymphoma
Inflammation

Pathways

Antibody-dependent Cellular Cytotoxicity
Pathogenesis
Glycosylation
Immune Response
Complement-dependent Cytotoxicity
Phagocytosis
Macrophage Activation
Fucosylation
Cytokine Production
Hypersensitivity
Secretion
Inflammatory Response
Cell Proliferation

Immune Complex Clearance
Anaphylaxis
Viral Replication
Cell Activation
Chemokine Production
Type Iii Hypersensitivity
Aging

PTMs

Glycosylation
Citrullination

Biotinylation
Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCGR3B

References

PMID: 2526846 by Ravetch J.V., et al. Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions.

PMID: 2967436 by Simmons D., et al. The Fc gamma receptor of natural killer cells is a phospholipid- linked membrane protein.