F2RL1 Antibodies

AND F2RL1 ELISA kits, F2RL1 Proteins

Many biological assays use antibodies to detect F2RL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with F2RL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop F2RL1 antibodies...

We validate the specificity of these antibodies to F2RL1 by testing them on tissues known to express F2RL1 positively and negatively. Browse below to find the F2RL1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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F2RL1 Infographic by Boster Bio

All F2RL1 Products

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Product

Figures

Specificity

Applications

Price

Anti-PAR2/F2RL1 Antibody Picoband®

1 Citations 7 Q&As

Human

$370
Cat # PB9700
100 μg/vial

Anti-PAR2 F2RL1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A01081
100ul

Anti-PAR2 Rabbit Monoclonal Antibody

+14

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01081
100 μl/vial

F2RL1 Overview

Facts about Proteinase-activated receptor 2.

F2RL1 3D structure. Source: alphafold

Proteinase-activated receptor 2 (F2RL1)

Receptor for trypsin and trypsin-like enzymes coupled to G proteins (PubMed:28445455). Its function is mediated through the activation of several signaling pathways such as phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho (PubMed:28445455).

May also be transactivated by cleaved F2R/PAR1. Involved in modulation of inflammatory reactions and regulation of innate and adaptive immunity, and functions as a sensor for proteolytic enzymes generated during infection.

Gene Information

Human
Gene Name:	F2RL1
Uniprot:	P55085
Entrez:	2150

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

CFIIRL1; coagulation factor II (thrombin) receptor-like 1; Coagulation factor II receptor-like 1; F2RL1; GPCR11; GPR11protease-activated receptor 2; G-protein coupled receptor 11; PAR2; PAR-2; PAR2G protein-coupled receptor-11; proteinase-activated receptor 2; proteinase-activated receptor-2; Thrombin receptor-like 1

Molecular Weight

Mass (kDA):
44.126 kDA

Genomic Context


Human

Location:	5q13.3
Sequence:	5; NC_000005.10 (76819030..76835315)

Tissue Specificity

Widely expressed in tissues with especially high levels in pancreas, liver, kidney, small intestine, and colon (PubMed:7556175, PubMed:8615752). Moderate expression is detected in many organs, but none in brain or skeletal muscle (PubMed:7556175, PubMed:8615752). Expressed in endothelial cells (PubMed:23202369).