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- Table of Contents
Facts about Proteinase-activated receptor 3.
Human | |
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Gene Name: | F2RL2 |
Uniprot: | O00254 |
Entrez: | 2151 |
Belongs to: |
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G-protein coupled receptor 1 family |
Coagulation Factor II Receptor-like 2; F2RL2; PAR3; Protease-activated receptor 3; Thrombin Receptor-Like 2
Mass (kDA):
42.508 kDA
Human | |
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Location: | 5q13.3 |
Sequence: | 5; NC_000005.10 (76615482..76623403, complement) |
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.
Cell membrane; Multi-pass membrane protein.
PMID: 9087410 by Ishihara H., et al. Protease-activated receptor 3 is a second thrombin receptor in humans.
PMID: 9614115 by Schmidt V.A., et al. The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a PAR gene cluster and characterization in vascular endothelial cells and platelets.