This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about ETS-related transcription factor Elf-1.
Binds specifically to 2 purine-rich themes from the HIV-2 enhancer. .
Human | |
---|---|
Gene Name: | ELF1 |
Uniprot: | P32519 |
Entrez: | 1997 |
Belongs to: |
---|
ETS family |
E74-like factor 1 (ets domain transcription factor); E74-like factor 1; ETS-related transcription factor Elf-1
Mass (kDA):
67.498 kDA
Human | |
---|---|
Location: | 13q14.11 |
Sequence: | 13; NC_000013.11 (40931919..41061386, complement) |
In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
Nucleus.
PMID: 1527846 by Leiden J.M., et al. A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells.
PMID: 1545787 by Thompson C.B., et al. Cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.