ELF2 Antibodies

AND ELF2 ELISA kits, ELF2 Proteins

Many biological assays use antibodies to detect ELF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ELF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ELF2 antibodies...

We validate the specificity of these antibodies to ELF2 by testing them on tissues known to express ELF2 positively and negatively. Browse below to find the ELF2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ELF2 Infographic by Boster Bio

All ELF2 Products

Product

Figures

Specificity

Applications

Price

Anti-ELF2 Antibody

Human, Mouse, Rat

$405
Cat # A03706
100ul

ELF2 (NM_201999) Human Over-expression Lysate

Human

$960
Cat # LS001998
100 µg

ELF2 Overview

Facts about ETS-related transcription factor Elf-2.

ELF2 3D structure. Source: alphafold

ETS-related transcription factor Elf-2 (ELF2)

Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter. .

Gene Information

Human
Gene Name:	ELF2
Uniprot:	Q15723
Entrez:	1998

Family

Belongs to:

ETS family

Alternative Names

b; E74-like factor 2 (ets domain transcription factor); E74-like factor 2; ets family transcription factor ELF2C; ETS-related transcription factor Elf-2; NERF-1a; NERF-1B; NERF-2; NERFEU32; New ETS-related factor

Molecular Weight

Mass (kDA):
63.967 kDA

Genomic Context


Human

Location:	4q31.1
Sequence:	4; NC_000004.12 (139057220..139177218, complement)

Tissue Specificity

Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes.

Subcellular Localizations

Nucleus.

Diseases

Endoplasmic Reticulum Stress
Leukemia
Malignant Neoplasms
Neoplasms
Neurodegenerative Disorders
Tumor Angiogenesis
Mammary Neoplasms
Sclerosis
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Fibrosis
Myeloid Leukemia
Skin Sensitisation

Hepatitis
Hepatitis C
Diabetes Mellitus
Physiological Stress
Contact Dermatitis
Metaplastic Cell Transformation
Chromosomal Translocation

Interacting Proteins

RUNX1

Pathways

Translation
Cell Death
Angiogenesis
Pathogenesis
Shoot Development
Sensitization
Blood Vessel Development
Cell Growth
Viral Replication
Transport
Regulation Of Shoot Development
Flower Development
Aging

Virulence
Myelination
Inflammatory Response
T Cell Proliferation
Oncogenesis
Cell Proliferation
Cell Development

PTMs

Phosphorylation
Cleavage

Dephosphorylation
Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ELF2

References

PMID: 8756667 by Oettgen P., et al. Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1.

PMID: 10207087 by Mao S., et al. Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.