EIF4G2 Antibodies

AND EIF4G2 ELISA kits, EIF4G2 Proteins

Many biological assays use antibodies to detect EIF4G2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF4G2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF4G2 antibodies...

We validate the specificity of these antibodies to EIF4G2 by testing them on tissues known to express EIF4G2 positively and negatively. Browse below to find the EIF4G2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF4G2 Infographic by Boster Bio

All EIF4G2 Products

Product

Figures

Specificity

Applications

Price

Anti-DAP-5 (N65) EIF4G2 Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A03888
100ul

Anti-P97/DAP5/EIF4G2 Antibody Picoband™

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03888-1
100 μg/vial

DAP5 (EIF4G2) (NM_001418) Human Over-expression Lysate

Human

$628
Cat # LS001982
100 µg

Anti-P97/DAP5/EIF4G2 Antibody Picoband™

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03888-2
100 µg/vial

EIF4G2 Overview

Facts about Eukaryotic translation initiation factor 4 gamma 2.

EIF4G2 3D structure. Source: alphafold

Eukaryotic translation initiation factor 4 gamma 2 (EIF4G2)

Appears to play a role in the change from cap-dependent into IRES-mediated translation during mitosis, apoptosis and viral disease. Cleaved by some caspases and viral proteases.

Gene Information

Human
Gene Name:	EIF4G2
Uniprot:	P78344
Entrez:	1982

Family

Belongs to:

eukaryotic initiation factor 4G family

Alternative Names

aging-associated protein 1; DAP-5; DAP5AAG1; Death-associated protein 5; eIF4G 2; eIF-4G 2; eIF-4-gamma 2; eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4 gamma, 2; eukaryotic translation initiation factor 4G-like 1; FLJ41344; NAT1; p97

Molecular Weight

Mass (kDA):
102.362 kDA

Genomic Context


Human

Location:	11p15.4
Sequence:	11; NC_000011.10 (10797046..10809035, complement)

Tissue Specificity

Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney.

Diseases

Neoplasms
Foot-and-mouth Disease
Malignant Neoplasms
Leukemia
Growth Arrest
Picornaviridae Infections
Carcinoma
Immunologic Deficiency Syndromes
Hiv Infections
Carcinoma, Transitional Cell
Neoplasm Metastasis
Malignant Neoplasm Of Breast

Ataxia
Leukoencephalopathies
Hypoxia
Stomatitis
Leukoencephalopathy With Vanishing White Matter
Malignant Neoplasm Of Urinary Bladder
Patient Dependence On

Interacting Proteins

EIF2S2
EIF4A1
HSPB1

Pathways

Translation
Cell Death
Cell Cycle
Mitosis
Proteolysis
Translational Initiation
Programmed Cell Death
Localization
Cell Differentiation
Hyperphosphorylation
Cell Proliferation
Induction Of Apoptosis
Glycosylation

Dna Repair
Mesoderm Formation
M Phase
Spermatid Differentiation
Spermatogenesis
Cell Cycle Arrest
Meiotic Cell Cycle

PTMs

Cleavage

Phosphorylation

Glycosylation

Research Areas

Apoptosis
mTOR Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF4G2

References

PMID: 9049310 by Imataka H., et al. A new translational regulator with homology to eukaryotic translation initiation factor 4G.

PMID: 9030685 by Yamanaka S., et al. A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA- editing enzyme.