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SERPINB1 Antibodies
AND SERPINB1 ELISA kits, SERPINB1 Proteins
Many biological assays use antibodies to detect SERPINB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SERPINB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SERPINB1 antibodies...
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SERPINB1 Infographic by Boster Bio
All SERPINB1 Products
Product
Figures
Specificity
Applications
Price
Dog, Human, Rat
Flow Cytometry, IHC, WB
$523
Cat # M04491
100 µl
Cat # M04491
100 µl
Dog, Human, Monkey
Flow Cytometry, IF, WB
$523
Cat # M04491-1
100 µl
Cat # M04491-1
100 µl
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04491-2
100 μg/vial
Cat # A04491-2
100 μg/vial
SERPINB1 Overview
Facts about Leukocyte elastase inhibitor.
Leukocyte elastase inhibitor (SERPINB1)
Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | SERPINB1 |
| Uniprot: | P30740 |
| Entrez: | 1992 |
Family
| Belongs to: |
|---|
| serpin family |
Alternative Names
EILEI; ELANH2MNEI; elastase; leukocyte elastase inhibitor; Monocyte/neutrophil elastase inhibitor; Peptidase inhibitor 2; PI-2; PI2M/NEI; protease inhibitor 2 (elastase), monocyte/neutrophil derived; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; Serpin B1; serpin peptidase inhibitor, clade B (ovalbumin), member 1
Molecular Weight
Mass (kDA):
42.742 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p25.2 |
| Sequence: | 6; NC_000006.12 (2832332..2842012, complement) |
Subcellular Localizations
Secreted. Cytoplasm. Cytoplasmic granule.
Diseases
- Inflammation
- Lung Diseases
- Fibrosis
- Cystic Fibrosis
- Neoplasms
- Lung Injury
- Carcinoma
- Malignant Neoplasms
- Tissue Damage
- Infectious Lung Disorder
- Pseudomonas Aeruginosa Infection
- Neoplasm Metastasis
- Hemorrhage
Pathways
- Proteolysis
- Localization
- Cell Death
- Cytokine Production
- Cell Differentiation
- Pathogenesis
- Cell Migration
- Cornification
- Cell Development
- Cellular Homeostasis
- Immune Response
- Dna Methylation
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINB1
bosterbio.com/bosterbio-gene-info-cards/SERPINB1
References
PMID: 1376927 by Remold-O'Donnell E., et al. Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor.
PMID: 9630619 by Zeng W., et al. Structure and sequence of human M/NEI (monocyte/neutrophil elastase inhibitor), an Ov-serpin family gene.