EIF4EBP2 Antibodies

AND EIF4EBP2 ELISA kits, EIF4EBP2 Proteins

Many biological assays use antibodies to detect EIF4EBP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF4EBP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF4EBP2 antibodies...

We validate the specificity of these antibodies to EIF4EBP2 by testing them on tissues known to express EIF4EBP2 positively and negatively. Browse below to find the EIF4EBP2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF4EBP2 Infographic by Boster Bio

All EIF4EBP2 Products

Product

Figures

Specificity

Applications

Price

Human EIF4EBP2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ13542
Starting from 20ug

EIF4EBP2 (NM_004096) Human Over-expression Lysate

Human

$628
Cat # LS001979
100 µg

EIF4EBP2 Overview

Facts about Eukaryotic translation initiation factor 4E-binding protein 2.

EIF4EBP2 3D structure. Source: alphafold

Eukaryotic translation initiation factor 4E-binding protein 2 (EIF4EBP2)

Repressor of translation initiation involved in synaptic plasticity, learning and memory formation (By similarity). Regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation.

By comparison, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (PubMed:25533957). EIF4EBP2 is enriched in brain and acts as a regulator of synapse activity and neuronal stem cell renewal through its ability to repress translation initiation (By similarity).

Gene Information

Human
Gene Name:	EIF4EBP2
Uniprot:	Q13542
Entrez:	1979

Family

Belongs to:

eIF4E-binding protein family

Alternative Names

4EBP2; 4E-BP2; eIF4E-binding protein 2; eukaryotic translation initiation factor 4E binding protein 2; eukaryotic translation initiation factor 4E-binding protein 2; PHASII; phosphorylated, heat and acid stable regulated by insulin protein II