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- Table of Contents
Facts about Ephrin-A3.
The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). .
Human | |
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Gene Name: | EFNA3 |
Uniprot: | P52797 |
Entrez: | 1944 |
Belongs to: |
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ephrin family |
EFL2; EFL-2; EFNA3; Ehk1-L; EPH-related receptor tyrosine kinase ligand 3; EphrinA3; Ephrin-A3; EPLG3EHK1 ligand; LERK3; LERK3LERK-3; ligand of eph-related kinase 3
Mass (kDA):
26.35 kDA
Human | |
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Location: | 1q21.3 |
Sequence: | 1; NC_000001.11 (155078837..155087538) |
Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.
Cell membrane; Lipid-anchor, GPI-anchor.
PMID: 7838529 by Kozlosky C.J., et al. Ligands for the receptor tyrosine kinases hek and elk: isolation of cDNAs encoding a family of proteins.
PMID: 7973638 by Davis S., et al. Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity.