Ephrin-A4 Antibodies

AND EFNA4 ELISA kits, Ephrin-A4 Proteins

Many biological assays use antibodies to detect Ephrin-A4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ephrin-A4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ephrin-A4 antibodies...

We validate the specificity of these antibodies to Ephrin-A4 by testing them on tissues known to express EFNA4 positively and negatively. Browse below to find the EFNA4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EFNA4 Infographic by Boster Bio

All EFNA4 Products

Product

Figures

Specificity

Applications

Price

Anti-Ephrin-A4 EFNA4 Antibody

5 Q&As

Human, Mouse

$399
Cat # A09230
100μl

EFNA4 Colorimetric Cell-Based ELISA Kit

Human, Mouse

ELISA

$480
Cat # EKC1182
1 kit, containing one 96-well plate and all necessary reagents

Ephrin A4 (EFNA4) (NM_005227) Human Over-expression Lysate

Human

$628
Cat # LS001945
100 µg

EFNA4 Overview

Facts about Ephrin-A4.

EFNA4 3D structure. Source: alphafold

Ephrin-A4 (EFNA4)

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, resulting in contact-dependent bidirectional signaling into neighboring cells.

May play a role in the interaction between activated B-lymphocytes and dendritic cells . .

Gene Information

Human
Gene Name:	EFNA4
Uniprot:	P52798
Entrez:	1945

Family

Belongs to:

ephrin family

Alternative Names

EFL4; EFL-4; EFNA4; EPH-related receptor tyrosine kinase ligand 4; EphrinA4; Ephrin-A4; EPLG4MGC125826; LERK-4; LERK4FLJ57652; ligand of eph-related kinase 4

Molecular Weight

Mass (kDA):
22.386 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (155063740..155069553)

Tissue Specificity

Expressed in the adult spleen, lymph node, prostate, ovary, small intestine, and colon, and in fetal heart, lung, liver and kidney. Also detected in hematopoietic cell lines.

Subcellular Localizations

[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 2]: Secreted.

Diseases

Tissue Adhesions
Chronic Lymphocytic Leukemia
Leukemia
Lymphoid Leukemia
Malignant Neoplasms
Neoplasms
Craniosynostosis
Congenital Abnormality
Congenital Abnormal Synostosis
Clinodactyly
Moderate Mental Retardation
Extravasation
Malignant Neoplasm Of Brain

Low Set Ears
Malignant Tumor Of Colon
Carcinoma
Carcinogenesis
Nervousness
Malignant Neoplasm Of Pancreas
Colorectal Cancer

Pathways

Cell Adhesion
Regeneration
Cell Migration
Chemotaxis
Tissue Regeneration
System Development
Cornification
Cell Cycle

Nervous System Development
Proteolysis
Pathogenesis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EFNA4

References

PMID: 7838529 by Kozlosky C.J., et al. Ligands for the receptor tyrosine kinases hek and elk: isolation of cDNAs encoding a family of proteins.

PMID: 10607706 by Aasheim H.-C., et al. A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes.