Draxin Antibodies

AND Draxin ELISA kits, Draxin Proteins

Many biological assays use antibodies to detect Draxin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Draxin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Draxin antibodies...

We validate the specificity of these antibodies to Draxin by testing them on tissues known to express Draxin positively and negatively. Browse below to find the Draxin antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Draxin Infographic by Boster Bio

All Draxin Products

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Specificity

Applications

Price

Anti-NEUCRIN DRAXIN Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A09941
0.1 mg

C1orf187 (DRAXIN) (NM_198545) Human Over-expression Lysate

Human

$628
Cat # LS374946
100 µg

Draxin Overview

Facts about Draxin.

Draxin

Chemorepulsive axon guidance protein needed for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development.

Willing to neutralize or neutralize neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) through its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

Gene Information

Mouse
Gene Name:	Draxin
Uniprot:	Q6PAL1
Entrez:	70433

Family

Belongs to:

draxin family

Alternative Names

AGPA3119; C1orf187; chromosome 1 open reading frame 187; dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; Draxin; FLJ34999; MGC117222; Neucrin; UNQ3119

Molecular Weight

Mass (kDA):
38.363 kDA

Genomic Context


Mouse

Location:	4\|4 E2
Sequence:	4;

Tissue Specificity

Predominantly expressed in developing neural tissues. Expressed in many brain regions, including the olfactory bulb, cortex, midbrain, cerebellum and pontine nuclei in postnatal day 0 (P0). Detected in the dorsal spinal cord and commissural axons. In the forebrain commissures, it is expressed in the regions that surround the corpus callosum, hippocampal commissure, and anterior commissure, such as the midline glial cells, indusium griseum glia, and glial wedge.

Diseases

Nervousness
Congenital Absence
Malignant Neoplasms
Down Syndrome
Tissue Adhesions
Colorectal Cancer
Agenesis Of Corpus Callosum

Crest Syndrome

Pathways

Axon Guidance
Cell Adhesion
Cell Division
Cell Migration
Cell Proliferation
Neural Crest Cell Migration

Localization

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Draxin

References

PMID: 19857465 by Miyake A., et al. Neucrin is a novel neural-specific secreted antagonist to canonical Wnt signaling.

PMID: 19150847 by Islam S.M., et al. Draxin, a repulsive guidance protein for spinal cord and forebrain commissures.