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Inverted formin-2 Antibodies
AND INF2 ELISA kits, Inverted formin-2 Proteins
Many biological assays use antibodies to detect Inverted formin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Inverted formin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Inverted formin-2 antibodies...
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INF2 Infographic by Boster Bio
All INF2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02710-1
100 μg/vial
Cat # A02710-1
100 μg/vial
INF2 Overview
Facts about Inverted formin-2.
Inverted formin-2 (INF2)
Severs actin filaments and hastens their polymerization and depolymerization. .
.
Gene Information
| Human | |
|---|---|
| Gene Name: | INF2 |
| Uniprot: | Q27J81 |
| Entrez: | 64423 |
Family
| Belongs to: |
|---|
| formin homology family |
Alternative Names
C14orf151; C14orf173DKFZp762A0214; chromosome 14 open reading frame 151; chromosome 14 open reading frame 173; FLJ22056; FSGS5; HBEAG-binding protein 2 binding protein C; HBEBP2-binding protein C; inverted formin, FH2 and WH2 domain containing; inverted formin-2; MGC13251; pp9484
Molecular Weight
Mass (kDA):
135.624 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q32.33 |
| Sequence: | 14; NC_000014.9 (104689606..104722535) |
Tissue Specificity
Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells.
Subcellular Localizations
Cytoplasm, perinuclear region.
Diseases
- Segmental Glomerulosclerosis
- Glomerulosclerosis (disorder)
- Focal Glomerulosclerosis
- Kidney Diseases
- Nephrotic Syndrome
- Kidney Failure, Chronic
- Charcot-marie-tooth Disease
- Inflammation
- Malignant Neoplasms
- Neoplasms
- Adenocarcinoma
- Malignant Neoplasm Of Lung
Pathways
- Sulfate Reduction
- Fermentation
- Methanogenesis
- Photosynthesis
- Localization
- Cell Growth
- Transport
- Cell Adhesion
- Sulfur Oxidation
- Ammonia Oxidation
- Transcytosis
- Nitrogen Fixation
- Demethylation
PTMs
- Oxidation
- Nitration
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INF2
bosterbio.com/bosterbio-gene-info-cards/INF2
References
PMID: 20023659 by Brown E.J., et al. Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis.
PMID: 21258034 by Boyer O., et al. Mutations in INF2 are a major cause of autosomal dominant focal segmental glomerulosclerosis.