Dppa3 Antibodies

AND Dppa3 ELISA kits, Dppa3 Proteins

Many biological assays use antibodies to detect Dppa3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dppa3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dppa3 antibodies...

We validate the specificity of these antibodies to Dppa3 by testing them on tissues known to express Dppa3 positively and negatively. Browse below to find the Dppa3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Dppa3 Infographic by Boster Bio

All Dppa3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Stella DPPA3 Antibody

Human, Mouse, Rat

ELISA, WB

$449
Cat # A09073
0.1 mg

Human DPPA3 Recombinant Protein

SDS-PAGE, Denatured

$265
Cat # PROTQ6W0C5
Starting from 10ug

Stella (DPPA3) (NM_199286) Human Over-expression Lysate

Human

$628
Cat # LS359787
100 µg

Dppa3 Overview

Facts about Developmental pluripotency-associated protein 3.

Developmental pluripotency-associated protein 3 (Dppa3)

Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming from the zygote following fertilization. In zygotes, DNA demethylation occurs selectively from the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this procedure.

Participates in protection of DNA methylation from the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at'Lys-9' (H3K9me2) on maternal genome, and shields maternal genome from TET3-mediated conversion to 5hmC and following DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and doesn't include much H3K9me2 mark.

Gene Information

Mouse
Gene Name:	Dppa3
Uniprot:	Q8QZY3
Entrez:	73708

Family

Belongs to:

No superfamily

Alternative Names

developmental pluripotency associated 3; DPPA3 developmental pluripotency associated 3; Dppa3; Stella

Molecular Weight

Mass (kDA):
17.67 kDA

Genomic Context


Mouse

Location:	6\|6 F1
Sequence:	6;

Tissue Specificity

Expressed in the immature oocytes and in newborn ovaries. Subsequently detected in maturing oocytes and in preimplantation embryos. Expressed in pluripotent embryonic but not in differentiated somatic cells. Expressed in blastocysts, epiblasts, primordial germ cells, embryonic gonads and primitive spermatogonia. No expression is detected in adult testes.