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- Table of Contents
Facts about Tubulin beta-2B chain.
Plays a crucial role in proper axon guidance in both peripheral and central axon tracts. Implicated in neuronal migration.
Mouse | |
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Gene Name: | Tubb2b |
Uniprot: | Q9CWF2 |
Entrez: | 73710 |
Belongs to: |
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tubulin family |
bA506K6.1; class II beta-tubulin isotype; DKFZp566F223; FLJ98847; MGC8685; tubulin beta-2B chain; tubulin, beta 2B; tubulin, beta polypeptide paralog
Mass (kDA):
49.953 kDA
Mouse | |
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Location: | 13|13 A3.3 |
Sequence: | 13; |
Strong expression is detected in the developing cortex and peripheral nervous system, as well as in the adult cerebellum, hippocampus and olfactory bulb.
PMID: 15890843 by Janke C., et al. Tubulin polyglutamylase enzymes are members of the TTL domain protein family.
PMID: 19465910 by Jaglin X.H., et al. Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria.