This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about CUGBP Elav-like family member 6.
Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
Human | |
---|---|
Gene Name: | CELF6 |
Uniprot: | Q96J87 |
Entrez: | 60677 |
Belongs to: |
---|
CELF/BRUNOL family |
CUGBP Elav-like family member 6
Mass (kDA):
50.477 kDA
Human | |
---|---|
Location: | 15q23 |
Sequence: | 15; NC_000015.10 (72284727..72320157, complement) |
Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney.
Nucleus. Cytoplasm.
PMID: 10893231 by Good P.J., et al. A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.
PMID: 14761971 by Ladd A.N., et al. CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing.