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Cytochrome P450 2J2 Antibodies
AND CYP2J2 ELISA kits, Cytochrome P450 2J2 Proteins
Many biological assays use antibodies to detect Cytochrome P450 2J2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 2J2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 2J2 antibodies...
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CYP2J2 Infographic by Boster Bio
All CYP2J2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$480
Cat # EKC1914
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1914
1 kit, containing one 96-well plate and all necessary reagents
Human
Flow Cytometry, IF, WB
$523
Cat # M03128-1
100 µl
Cat # M03128-1
100 µl
Human
IHC, WB
$523
Cat # M03128
100 µl
Cat # M03128
100 µl
CYP2J2 Overview
Facts about Cytochrome P450 2J2.
Cytochrome P450 2J2 (CYP2J2)
This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP2J2 |
| Uniprot: | P51589 |
| Entrez: | 1573 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
Arachidonic acid epoxygenase; CPJ2; CYPIIJ2; cytochrome P450 2J2; cytochrome P450, family 2, subfamily J, polypeptide 2; cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2; EC 1.14.14.1; flavoprotein-linked monooxygenase; microsomal monooxygenase
Molecular Weight
Mass (kDA):
57.611 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p32.1 |
| Sequence: | 1; NC_000001.11 (59893308..59926798, complement) |
Tissue Specificity
Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.
Subcellular Localizations
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Diseases
- Hypertensive Disease
- Malignant Neoplasms
- Inflammation
- Neoplasms
- Cardiovascular Diseases
- Reperfusion Injury
- Ischemia
- Carcinoma
- Infarction
- Heart Diseases
- Coronary Artery Disease
- Tumor Angiogenesis
Pathways
- Transport
- Pathogenesis
- Excretion
- Cell Proliferation
- Ion Transport
- Angiogenesis
- Localization
- Cell Growth
- Secretion
- Cell Adhesion
- Cell Migration
- Tube Formation
- Vasodilation
PTMs
- Hydroxylation
- Oxidation
- Demethylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP2J2
bosterbio.com/bosterbio-gene-info-cards/CYP2J2
References
PMID: 8631948 by Wu S., et al. Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart.
PMID: 12386130 by Matsumoto S., et al. Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole.