Cytochrome P450 3A5 Antibodies

AND CYP3A5 ELISA kits, Cytochrome P450 3A5 Proteins

Many biological assays use antibodies to detect Cytochrome P450 3A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 3A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 3A5 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 3A5 by testing them on tissues known to express CYP3A5 positively and negatively. Browse below to find the CYP3A5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP3A5 Infographic by Boster Bio

All CYP3A5 Products

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Specificity

Applications

Price

Anti-Cytochrome P450 3A5 CYP3A5 Antibody

Human, Mouse, Rat

$405
Cat # A00530
100ul

Cytochrome P450 3A5 (CYP3A5) (NM_000777) Human Recombinant Protein

$1062
Cat # PROTP20815
20 µg

Anti-CYP3A5 Antibody (C-term)

Human

IF, IHC-P, WB

$299
Cat # A00530-1
80 µl

Cytochrome P450 3A5 (CYP3A5) (NM_000777) Human Over-expression Lysate

Human

$628
Cat # LS001577
100 µg

CYP3A5 Overview

Facts about Cytochrome P450 3A5.

CYP3A5 3D structure. Source: alphafold

Cytochrome P450 3A5 (CYP3A5)

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.

It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. .

Gene Information

Human
Gene Name:	CYP3A5
Uniprot:	P20815
Entrez:	1577

Family

Belongs to:

cytochrome P450 family

Alternative Names

aryl hydrocarbon hydroxylase; CP35; CYPIIIA5; cytochrome P450 3A5; Cytochrome P450 HLp2; cytochrome P-450; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; Cytochrome P450-PCN3; DKFZp686L16231; EC 1.14.14.1; flavoprotein-linked monooxygenase; microsomal monooxygenase; niphedipine oxidase; P450PCN3FLJ31317; PCN3; xenobiotic monooxygenase

Molecular Weight

Mass (kDA):
57.109 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (99648194..99679996, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Hiv Infections
Mammary Neoplasms
Hypertensive Disease
Leukemia
Cholangiocarcinoma
Carcinoma
Dysequilibrium Syndrome
Malignant Neoplasm Of Prostate
Decreased Immunologic Activity [pe]

Medication Reaction
Malignant Neoplasm Of Lung
Carcinogenesis
Kidney Diseases
Immunologic Deficiency Syndromes
Prostatic Neoplasms
Acute Lymphocytic Leukemia

Pathways

Transport
Excretion
Glomerular Filtration
Platelet Aggregation
Drug Resistance
Drug Transport
Localization
Pathogenesis
Demethylation
Conjugation
Dna Repair
Immune Response
Reverse Transcription

Translation
Methylation
Secretion
Mrna Splicing
Cell Growth
Rna Interference
Regeneration

PTMs

Hydroxylation
Oxidation
Demethylation
Phosphorylation
Cleavage

Methylation
Deacetylation
Decarboxylation
Acetylation
Ubiquitination

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP3A5

References

PMID: 2802615 by Schuetz J.D., et al. Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver.

PMID: 11266076 by Gellner K., et al. Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.