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- Table of Contents
Facts about Catenin delta-2.
It probably acts on beta- catenin turnover, easing beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (By similarity). Functions as a transcriptional activator when bound to ZBTB33 (By similarity).
Human | |
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Gene Name: | CTNND2 |
Uniprot: | Q9UQB3 |
Entrez: | 1501 |
Belongs to: |
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beta-catenin family |
catenin (cadherin-associated protein), delta 2 (neural plakophilin-relatedarm-repeat protein); catenin delta-2; Delta-catenin; GT24T-cell delta-catenin; Neural plakophilin-related ARM-repeat protein; Neurojungin; NPRAPneurojungin
Mass (kDA):
132.656 kDA
Human | |
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Location: | 5p15.2 |
Sequence: | 5; NC_000005.10 (10971836..11904446, complement) |
Expressed in brain; highest expression is observed in fetal brain (PubMed:25807484).
Nucleus. Cell junction, adherens junction. Cell projection, dendrite. Perikaryon.
PMID: 9223106 by Zhou J., et al. Presenilin 1 interaction in the brain with a novel member of the Armadillo family.
PMID: 9971746 by Lu Q., et al. Delta-catenin, an adhesive junction-associated protein which promotes cell scattering.