CTP synthase 1 (CTPS1)

This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP- dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen.

This enzyme and its product, CTP, play a vital role in the proliferation of activated lymphocytes and therefore in immunity. .