Crtam Antibodies

AND Crtam ELISA kits, Crtam Proteins

Many biological assays use antibodies to detect Crtam, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Crtam in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Crtam antibodies...

We validate the specificity of these antibodies to Crtam by testing them on tissues known to express Crtam positively and negatively. Browse below to find the Crtam antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Crtam Infographic by Boster Bio

All Crtam Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CRTAM Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08105
100ul

Human CRTAM Recombinant Protein

SDS-PAGE

$250
Cat # PROTO95727
Starting from 10ug

Human CRTAM ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2172
96 wells/kit, with removable strips.

CRTAM (NM_019604) Human Over-expression Lysate

Human

$628
Cat # LS056253
100 µg

Crtam Overview

Facts about Cytotoxic and regulatory T-cell molecule.

Cytotoxic and regulatory T-cell molecule (Crtam)

Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. .

Gene Information

Mouse
Gene Name:	Crtam
Uniprot:	Q149L7
Entrez:	54698

Family

Belongs to:

nectin family

Alternative Names

CD355 antigen; CD355; class I MHC restricted T cell associated molecule; class-I MHC-restricted T cell associated molecule; Class-I MHC-restricted T-cell-associated molecule; CRTAM; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule

Molecular Weight

Mass (kDA):
43.907 kDA

Genomic Context


Mouse

Location:	9 A5.1\|9 21.79 cM
Sequence:	9;

Tissue Specificity

In the immune system, expression is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. Also expressed in spleen, brain and testis.

Diseases

Tissue Adhesions
Neoplasms
Autoimmune Reaction
Malignant Neoplasms
Diabetes Mellitus
Autoimmune Diseases
Carcinoma
Diabetes, Autoimmune
Occlusion, Middle Cerebral Artery
Inflammatory Response
Malignant Neoplasm Of Lung
Myocardial Infarction

Asthma
Pituitary Diseases
Cerebral Artery Occlusion
Rheumatoid Arthritis
Celiac Disease
Cerebral Ischemia

Pathways

Secretion
Cell Adhesion
Immune Response
Cell Proliferation
Cytokine Secretion
Cell Division
Cell Activation
Thymus Development
T Cell Activation
Adaptive Immune Response
Leukocyte Differentiation
Nerve Development
Spermatogenesis

Inflammatory Response
Tolerance Induction
Cytokine Production
Translation
Locomotion
T Cell Proliferation
Regulation Of Immune Response

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Crtam

References

PMID: 10811014 by Kennedy J., et al. A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM).

PMID: 15811952 by Boles K.S., et al. The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM.