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RRN3 Antibodies
AND RRN3 ELISA kits, RRN3 Proteins
Many biological assays use antibodies to detect RRN3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RRN3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RRN3 antibodies...
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RRN3 Infographic by Boster Bio
All RRN3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IHC-P, WB, IF (paraffin)
$335
Cat # P05439
100ul
Cat # P05439
100ul
Human
ELISA
$480
Cat # EKC1564
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1564
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA
$540
Cat # EKC2627
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2627
1 kit, containing two 96-well plates and all necessary reagents
RRN3 Overview
Facts about RNA polymerase I-specific transcription initiation factor RRN3.
RNA polymerase I-specific transcription initiation factor RRN3 (RRN3)
Required for efficient transcription initiation by RNA polymerase I. Required for the creation of the competent preinitiation complex (PIC).
Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | RRN3 |
| Uniprot: | Q9NYV6 |
| Entrez: | 54700 |
Family
| Belongs to: |
|---|
| RRN3 family |
Alternative Names
DKFZp566E104; RNA polymerase I-specific transcription initiation factor RRN3; RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae); RRN3 RNA polymerase I transcription factor homolog (yeast); TIF-IA; TIFIAMGC104238; Transcription initiation factor IA; transcription initiation factor TIF-IA
Molecular Weight
Mass (kDA):
74.107 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p13.11 |
| Sequence: | 16; NC_000016.10 (15060022..15094335, complement) |
Subcellular Localizations
Nucleus, nucleolus.
Diseases
- Parkinson Disease
- Malignant Neoplasms
- Sclerosis
- Malnutrition
- Infectious Mononucleosis
- Neurodegenerative Disorders
- Nerve Degeneration
- Multiple Sclerosis
- Inflammatory Response
- Endoplasmic Reticulum Stress
- Multiple Sclerosis, Relapsing-remitting
- Neoplasms
Pathways
- Cell Growth
- Rrna Transcription
- Ribosome Biogenesis
- Translation
- Cell Cycle
- Interphase
- Localization
- Protein Phosphorylation
- Granulocyte Differentiation
- Hyperphosphorylation
- Hypersensitivity
- Cell Cycle Arrest
- Inflammatory Response
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RRN3
bosterbio.com/bosterbio-gene-info-cards/RRN3
References
PMID: 11265758 by Bodem J., et al. TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p.
PMID: 10758157 by Moorefield B., et al. RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human.