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- Table of Contents
Facts about Metal transporter CNNM2.
.
Human | |
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Gene Name: | CNNM2 |
Uniprot: | Q9H8M5 |
Entrez: | 54805 |
Belongs to: |
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ACDP family |
cyclin M2; metal transporter CNNM2
Mass (kDA):
96.623 kDA
Human | |
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Location: | 10q24.32 |
Sequence: | 10; NC_000010.11 (102918293..103090222) |
Widely expressed. Expressed at higher level in brain, kidney and placenta, while it is weakly expressed in skeletal muscle. In the kidney, it is expressed in the distal convoluted tubule and the thick ascending limb of Henle loop.
Cell membrane; Multi-pass membrane protein.
PMID: 12657465 by Wang C.-Y., et al. Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP).
PMID: 21397062 by Stuiver M., et al. CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia.