Cbp/p300-interacting transactivator 4 (Cited4)

Acts as transcriptional coactivator for TFAP2/AP-2.

Improves estrogen-dependent transactivation mediated by estrogen receptors.

May be an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells.