CC2D1A Antibodies

AND CC2D1A ELISA kits, CC2D1A Proteins

Many biological assays use antibodies to detect CC2D1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CC2D1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CC2D1A antibodies...

We validate the specificity of these antibodies to CC2D1A by testing them on tissues known to express CC2D1A positively and negatively. Browse below to find the CC2D1A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CC2D1A Infographic by Boster Bio

All CC2D1A Products

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Product

Figures

Specificity

Applications

Price

Anti-CC2D1A Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A04775
100ul

Anti-CC2D1A Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M04775
100 μl/vial

CC2D1A (NM_017721) Human Over-expression Lysate

Human

$628
Cat # LS054862
100 µg

CC2D1A Overview

Facts about Coiled-coil and C2 domain-containing protein 1A.

CC2D1A 3D structure. Source: alphafold

Coiled-coil and C2 domain-containing protein 1A (CC2D1A)

Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE.

May play a role in the altered regulation of HTR1A related to stress and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell.

Gene Information

Human
Gene Name:	CC2D1A
Uniprot:	Q6P1N0
Entrez:	54862

Family

Belongs to:

CC2D1 family

Alternative Names

Akt kinase-interacting protein 1; coiled-coil and C2 domain containing 1A; coiled-coil and C2 domain-containing protein 1A; Five repressor element under dual repression-binding protein 1; FLJ20241; FLJ41160; FRE under dual repression-binding protein 1; FREUD-1; mental retardation, nonsyndromic, autosomal recessive, 3; MRT3Freud-1/Aki1; Putative NF-kappa-B-activating protein 023N; putative NFkB activating protein

Molecular Weight

Mass (kDA):
104.062 kDA

Genomic Context


Human

Location:	19p13.12
Sequence:	19; NC_000019.10 (13906149..13930879)

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Diseases

Major Depressive Disorder
Depressive Disorder
Mental Disorders
Mood Disorders
Immunologic Deficiency Syndromes
Stress, Psychological
Anxiety Disorders
Hiv Infections
Depression And Suicide
Hypokinesia

Nervousness
Cytogenetic Abnormality
Febrile Convulsions
Rna Virus Infections
Dysequilibrium Syndrome

Interacting Proteins

CHMP4B

Pathways

Localization
Transport
Gene Silencing
Induction Of Apoptosis
Brain Development
Mitosis
Glycosylation
Metaphase
Nuclear Export
Anaphase
Cell Division

Cytokine Production
Cell Cycle
Sister Chromatid Cohesion
Cell Differentiation
Lipid Binding
Membrane Fission

PTMs

Phosphorylation

Cleavage

Glycosylation

Research Areas

DNA Repair
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CC2D1A

References

PMID: 12761501 by Matsuda A., et al. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

PMID: 16033914 by Basel-Vanagaite L., et al. The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation.