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PPP1R14D Antibodies
AND PPP1R14D ELISA kits, PPP1R14D Proteins
Many biological assays use antibodies to detect PPP1R14D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP1R14D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP1R14D antibodies...
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PPP1R14D Overview
Facts about Protein phosphatase 1 regulatory subunit 14D.
Protein phosphatase 1 regulatory subunit 14D (PPP1R14D)
Inhibitor of PPP1CA.
Has inhibitory activity only when phosphorylated, developing a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contractions..
Gene Information
| Human | |
|---|---|
| Gene Name: | PPP1R14D |
| Uniprot: | Q9NXH3 |
| Entrez: | 54866 |
Family
| Belongs to: |
|---|
| PP1 inhibitor family |
Alternative Names
CPI17-like; FLJ20251; gastrointestinal and brain-specific PP1-inhibitory protein 1; GBPI; GBPI1; GBPI-1; gut and brain phosphatase inhibitor 1; MGC119014; MGC119016; PKC-dependent PP1 inhibitory protein; protein phosphatase 1 regulatory subunit 14D; protein phosphatase 1, regulatory (inhibitor) subunit 14D
Molecular Weight
Mass (kDA):
16.508 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q15.1 |
| Sequence: | 15; NC_000015.10 (40815451..40828793, complement) |
Tissue Specificity
Detected in colon, intestine, kidney and brain cortex.
Subcellular Localizations
Cytoplasm.
Diseases
- Cardiovascular Diseases
- Malignant Neoplasms
- Diabetes Mellitus, Experimental
- Neoplasms
- Nervous System Disorder
- Diabetes Mellitus
Pathways
- Protein Phosphorylation
- Transport
- Vesicle Transport
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP1R14D
bosterbio.com/bosterbio-gene-info-cards/PPP1R14D
References
PMID: 12974676 by Liu Q.-R., et al. GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA.