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- Table of Contents
Facts about Bardet-Biedl syndrome 12 protein.
As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.
Human | |
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Gene Name: | BBS12 |
Uniprot: | Q6ZW61 |
Entrez: | 166379 |
Belongs to: |
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TCP-1 chaperonin family |
Bardet-Biedl syndrome 12; chromosome 4 open reading frame 24; FLJ35630C4orf24Bardet-Biedl syndrome 12 protein; FLJ41559
Mass (kDA):
79.085 kDA
Human | |
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Location: | 4q27 |
Sequence: | 4; NC_000004.12 (122700437..122744943) |
Cell projection, cilium. Located within the basal body of the primary cilium of differentiating preadipocytes.
PMID: 19190184 by Marion V., et al. Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation.
PMID: 20080638 by Seo S., et al. BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.