Dclk2 Antibodies

AND Dclk2 ELISA kits, Dclk2 Proteins

Many biological assays use antibodies to detect Dclk2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dclk2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dclk2 antibodies...

We validate the specificity of these antibodies to Dclk2 by testing them on tissues known to express Dclk2 positively and negatively. Browse below to find the Dclk2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Dclk2 Infographic by Boster Bio

All Dclk2 Products

Product

Figures

Specificity

Applications

Price

Anti-DCLK2/Dcamkl2 Antibody

3 Q&As

Human, Mouse

$360
Cat # A09671
100 µl

DCLK2 Colorimetric Cell-Based ELISA

Human, Mouse

ELISA

$480
Cat # EKC1872
1 kit, containing one 96-well plate and all necessary reagents

Anti-DCLK2 Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A09671-1
0.1 mg

DCAMKL2 (DCLK2) (NM_001040260) Human Recombinant Protein

$1249
Cat # PROTQ8N568
20 µg

DCAMKL2 (DCLK2) (NM_001040260) Human Over-expression Lysate

Human

$960
Cat # LS166614
100 µg

Dclk2 Overview

Facts about Serine/threonine-protein kinase DCLK2.

Serine/threonine-protein kinase DCLK2 (Dclk2)

Protein kinase with a considerably reduced Ca(2+)+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm.

Gene Information

Mouse
Gene Name:	Dclk2
Uniprot:	Q6PGN3
Entrez:	70762

Family

Belongs to:

protein kinase superfamily

Alternative Names

CL2EC 2.7.11.1; CLICK-II; CLIK2; DCDC3; DCDC3BCaMK-like CREB regulatory kinase 2; DCK2DCAMKL2; DKFZp761I032; doublecortin and CaM kinase-like 2; Doublecortin domain-containing protein 3B; Doublecortin-like and CAM kinase-like 2; doublecortin-like kinase 2CLICK2; EC 2.7.11; MGC45428; serine/threonine-protein kinase DCLK2

Molecular Weight

Mass (kDA):
82.979 kDA

Genomic Context


Mouse

Location:	3\|3 F1
Sequence:	3;

Tissue Specificity

Expressed in the central and peripheral nervous system including the brain, spinal cord, cranial and dorsal root ganglia and in the parasympathetic ganglia. Present in neurons, but not in glial cells, in most forebrain areas. Strong expression in the hippocampal CA1 pyramidal cell layer. Expressed in the photoreceptor sensory cilium complex and in eyes. Also detected in individual cells of the olfactory epithelium.

Diseases

Lissencephaly
Epilepsy
Classical Lissencephaly
Autistic Disorder
Malnutrition
Inattention
Congenital Neurologic Anomalies
Nervous System Disorder

Attention Deficit Hyperactivity Disorder
Autism Spectrum Disorders
Intractable Epilepsy

Pathways

Brain Development

PTMs

Phosphoprotein

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dclk2

References

PMID: 16684769 by Ohmae S., et al. Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV.

PMID: 16869982 by Reiner O., et al. The evolving doublecortin (DCX) superfamily.